| Inbound Relationships | 
Type | 
Active | 
Source | 
Characteristic | 
Refinability | 
Group | 
| Flexible fibreoptic laryngoscopy with removal of lesion | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 3 | 
| pT3: Tumor more than 4 cm and/or tumor having extraparenchymal extension (major salivary glands) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| T3a: Prostate tumor with extracapsular extension (unilateral or bilateral) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Lymphoma involves multiple lymph node regions (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| pM1 (IV): Distant metastasis (TNM category and FIGO stage) (fallopian tube) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Diffusely infiltrative (linitis plastica) tumor configuration | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Bronchoscopic destruction of lesion - laser | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Biopsy of lesion of temporal lobe (procedure) | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Lymphoma stage IIIse | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Chemosurgery by Mohs' technique, second stage | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 3 | 
| Chemosurgery by Mohs' technique, second stage | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 4 | 
| Clubbing of nail | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 3 | 
| Tumor massively invades choroid (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Excision of tumor from elbow area, deep, intramuscular | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 4 | 
| Destruction of chorioretinal lesion by laser photocoagulation | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Biopsy of cranial lesion | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Destruction of lesion of retina by laser photocoagulation | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| pT3: Tumor invades pancreas (ampulla of Vater) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Distant metastasis cannot be assessed (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Rigid bronchoscopic laser destruction of lesion of trachea (procedure) | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Excision of lesion of tendon sheath of ankle (procedure) | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Chemical cauterization for destruction of lesion of uvula | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Drug-induced hair abnormality (disorder) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 3 | 
| International Federation of Gynecology and Obstetrics cervical cancer (FIGO CC) stage IB1 | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Biopsy of lesion of fascia | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| N2: Metastasis in 4 or more lymph nodes | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Gleason Score 5-6: Moderately differentiated | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Open cryotherapy to lesion of rectum | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Open biopsy of lesion of brain tissue | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Cryotherapy to lesion of anus | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Excision of lesion of umbilicus (procedure) | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Stereotactic radiosurgery of intracranial arteriovenous malformation | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| T3: Pancreatic tumor extends directly to any of the following: duodenum; bile duct; peripancreatic tissues | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Lesion of salivary gland | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| International neuroblastoma staging system stage 2B (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Open biopsy of lesion of stomach | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Tumor location cannot be determined (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Keratinisation of ocular surface | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| On examination - suppuration skin sinus | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| pT3: Tumor invades through the muscularis propria into the subserosa or into the nonperitonealized perimuscular tissue (mesentery or retroperitoneum) with extension 2 cm or less (small intestine) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| pT1: Tumor invades submucosa (appendix) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Great vessels involved by direct extension of malignant neoplasm (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| T2 (IIC): Trophoblast: gestational trophoblastic tumor extends outside of the uterus but limited to genital structures with two risk factors | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Lesion of vulva | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| High intensity focused ultrasound ablation of lesion of uterus (procedure) | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Percutaneous photodynamic therapy of lesion of bile duct (procedure) | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Open excision of lesion of urinary bladder | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| pT3b: Melanoma 2.01 to 4.0 mm in thickness, with ulceration (melanoma of the skin) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| T1: Tumor limited to ipsilateral parietal and/or visceral pleura | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Open destruction of lesion of duodenum | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Excision of lesion of bursa | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Tumor invasion by direct extension to other structures | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Thyroid TNM finding | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| International neuroblastoma pathology classification: Unfavorable histology group, patient less than 1.5 years old, with poorly differentiated or differentiating neuroblastoma (Schwannian stroma-poor) and high mitosis-karyorrhexis index (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Radiotherapy to lesion of peripheral nerve (procedure) | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Excision of lesion of kidney with partial nephrectomy | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 3 | 
| Aspiration of pancreatic lesion using ultrasonic guidance (procedure) | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 3 | 
| Birthmark | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 3 | 
| Resection of coarctation | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| pT2a (IIA): Tumor involves one or both fallopian tubes with extension and/or metastasis to the uterus and/or ovaries (TNM category and FIGO stage) (fallopian tube) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Nephroscopic resection of lesion in renal pelvis | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Breslow measurement - Invasion 0.76 to 1.5mm from deep border of granular layer | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| pT1 (I): Tumor confined to the vulva or vulva and perineum, 2 cm or less in greatest dimension (TNM category and FIGO stage) (vulva) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| On examination - milk spots | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Excision of lesion of urinary bladder (procedure) | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Excision of intradural lesion of base of anterior cranial fossa (procedure) | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| N1: Metastasis in regional lymph node or nodes | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Dukes stage B (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Stereotactic radiosurgery of intracranial venous malformation | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Percutaneous embolization of lesion of kidney using fluoroscopic guidance with contrast (procedure) | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Percutaneous embolization of lesion of kidney using fluoroscopic guidance with contrast (procedure) | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 3 | 
| pT4a: Tumor invades thyroid/cricoid cartilage, hyoid bone, thyroid gland, esophagus or central compartment of soft tissue (hypopharynx) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Epithelial ovarian tumor, International Federation of Gynecology and Obstetrics stage IC | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Excisional biopsy of lesion of esophagus | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Escharectomy | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Tumor pigmentation, diffuse (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| T4: Aerodigestive tract tumor invades adjacent structures (thyroid/cricoid cartilage, carotid artery, soft tissues of neck, prevertebral fascia/muscles, thyroid and/or esophagus) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Synchronous primary carcinomas (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| International Federation of Gynecology and Obstetrics cervical cancer stage Ib | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Laminectomy with excision of intraspinal lesion (procedure) | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 3 | 
| Lesion of ligaments of foot region | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| T3: Breast tumor >5 cm in greatest dimension | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Slap mark | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Procedure for lung lesion | 
Procedure morphology (attribute) | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Excision of skin lesion and Z-plasty (procedure) | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Tumor invades muscle (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Lymphoma stage finding (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Abnormal radiologic density, nodular | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 3 | 
| pT3a: Tumor invades optic nerve through the level of the lamina cribrosa but not to the line of resection (retinoblastoma) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Destruction of lesion of retina by xenon arc photocoagulation | 
Direct morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Lymphatic (small vessel) extramural invasion by tumor present (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Fissure of prepuce | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Percutaneous radiofrequency ablation of lesion of lung (procedure) | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Hyperplasia of cervix | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| T2 (II): Endometrial tumor invades cervix, but does not extend beyond uterus | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Perineural invasion by tumor not identified (finding) | 
Associated morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Biopsy of lesion of occipital lobe (procedure) | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| pM1 (IVB): Distant metastasis (TNM category and FIGO stage) (uterine cervix) | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Epithelial ovarian tumour, FIGO stage IVB | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 1 | 
| Capillary fragility abnormality | 
Associated morphology | 
False | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 2 | 
| Excision of lesion of tarsal and metatarsal | 
Direct morphology | 
True | 
Lesion (morphologic abnormality) | 
Inferred relationship | 
Some | 
 3 |