702806008: Ruxolitinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Substance with enzyme inhibitor mechanism of action\Substance with transferase inhibitor mechanism of action\Substance with phosphotransferase inhibitor mechanism of action\Substance with protein kinase inhibitor mechanism of action\Substance with protein-tyrosine kinase inhibitor mechanism of action\Substance with Janus kinase inhibitor mechanism of action\Ruxolitinib

\Drug or medicament\Antineoplastic agent\Ruxolitinib
\Drug or medicament\Pyrazole derivative\Ruxolitinib

\Substance categorized by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound\Nitrogen compound\Organic nitrogen compound\...

\Azole\Pyrazole and/or pyrazole derivative\Pyrazole derivative\Ruxolitinib

\Nitrile\Ruxolitinib

\Organic compound\Organic cyclic compound\Heterocyclic compound\Azole\Pyrazole and/or pyrazole derivative\Pyrazole derivative\Ruxolitinib
\Organic compound\Organic nitrogen compound\Azole\Pyrazole and/or pyrazole derivative\Pyrazole derivative\Ruxolitinib
\Organic compound\Organic nitrogen compound\Nitrile\Ruxolitinib
\Organic compound\Hydrocarbon\Pyrazole and/or pyrazole derivative\Pyrazole derivative\Ruxolitinib

Status: current, Not sufficiently defined by necessary conditions definition status. Date: 31-Jul 2014. Module: SNOMED CT core module

Descriptions:

Id Description Lang Type Status Case? Module

3006149011 Ruxolitinib en Synonym Active Entire term case insensitive SNOMED CT core module

3006175010 Ruxolitinib (substance) en Fully specified name Active Entire term case insensitive SNOMED CT core module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Ruxolitinib	Is a	Substance with protein-tyrosine kinase inhibitor mechanism of action	false	Inferred relationship	Existential restriction modifier
Ruxolitinib	Is a	Antineoplastic agent	true	Inferred relationship	Existential restriction modifier
Ruxolitinib	Is a	Substance with Janus kinase inhibitor mechanism of action	true	Inferred relationship	Existential restriction modifier
Ruxolitinib	Has disposition	Janus kinase inhibitor	true	Inferred relationship	Existential restriction modifier
Ruxolitinib	Is a	Chemical categorized functionally	false	Inferred relationship	Existential restriction modifier
Ruxolitinib	Is a	Substance with enzyme inhibitor mechanism of action	false	Inferred relationship	Existential restriction modifier
Ruxolitinib	Is a	Nitrile	true	Inferred relationship	Existential restriction modifier
Ruxolitinib	Is a	Pyrazole derivative	true	Inferred relationship	Existential restriction modifier

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing ruxolitinib	Has active ingredient	True	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 5 milligram/1 each conventional release oral tablet	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Product containing precisely ruxolitinib 10 milligram/1 each conventional release oral tablet	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Product containing precisely ruxolitinib 20 milligram/1 each conventional release oral tablet	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Product containing precisely ruxolitinib 15 milligram/1 each conventional release oral tablet	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Product containing precisely ruxolitinib 25 milligram/1 each conventional release oral tablet	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Product containing precisely ruxolitinib 5 milligram/1 each conventional release oral tablet	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 5 milligram/1 each conventional release oral tablet	Has basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 10 milligram/1 each conventional release oral tablet	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 10 milligram/1 each conventional release oral tablet	Has basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 20 milligram/1 each conventional release oral tablet	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 20 milligram/1 each conventional release oral tablet	Has basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 15 milligram/1 each conventional release oral tablet	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 15 milligram/1 each conventional release oral tablet	Has basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 25 milligram/1 each conventional release oral tablet	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 25 milligram/1 each conventional release oral tablet	Has basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Ruxolitinib phosphate	Is a	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Product containing precisely ruxolitinib 5 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 10 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 20 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 15 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 25 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing ruxolitinib in oral dose form (medicinal product form)	Has active ingredient	True	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Ruxolitinib phosphate	Is modification of	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib	Has active ingredient	True	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing only ruxolitinib in oral dose form (medicinal product form)	Has active ingredient	True	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib (as ruxolitinib phosphate) 5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib (as ruxolitinib phosphate) 10 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib (as ruxolitinib phosphate) 20 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib (as ruxolitinib phosphate) 15 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib (as ruxolitinib phosphate) 25 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Ruxolitinib withdrawal syndrome	Associated with	False	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Ruxolitinib dependence	Causative agent	True	Ruxolitinib	Inferred relationship	Existential restriction modifier	1
Product containing precisely ruxolitinib 5 milligram/1 each conventional release oral tablet	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Product containing precisely ruxolitinib 10 milligram/1 each conventional release oral tablet	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 5mg tablets	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 10mg tablets	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 10mg tablets	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 5mg tablets	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 15mg tablets (Novartis Pharmaceuticals UK Ltd) 56 tablet 4 x 14 tablets	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 20mg tablets (Novartis Pharmaceuticals UK Ltd) 56 tablet 4 x 14 tablets	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 20mg tablets (Novartis Pharmaceuticals UK Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 5mg tablets (Novartis Pharmaceuticals UK Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 15mg tablets	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 20mg tablets	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 5mg tablets	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 15mg tablets (Novartis Pharmaceuticals UK Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 5mg tablets 56 tablet	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 5mg tablets (Novartis Pharmaceuticals UK Ltd) 56 tablet 4 x 14 tablets	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 20mg tablets 56 tablet	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 15mg tablets 56 tablet	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 20mg tablets (Novartis Pharmaceuticals UK Ltd) 60 tablet	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 15mg tablets (Novartis Pharmaceuticals UK Ltd) 60 tablet	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 5mg tablets (Novartis Pharmaceuticals UK Ltd) 60 tablet	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 15mg tablets 60 tablet	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 5mg tablets 60 tablet	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 20mg tablets 60 tablet	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 15mg tablets	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 20mg tablets	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 5mg tablets	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 20mg tablets (Novartis Pharmaceuticals UK Ltd)	Has active ingredient	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 5mg tablets (Novartis Pharmaceuticals UK Ltd)	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 15mg tablets (Novartis Pharmaceuticals UK Ltd)	Has active ingredient	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Product containing precisely ruxolitinib 5 milligram/1 each conventional release oral tablet	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 10mg tablets (Novartis Pharmaceuticals UK Ltd)	Has active ingredient	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 10mg tablets 56 tablet	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Product containing precisely ruxolitinib 10 milligram/1 each conventional release oral tablet	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 10mg tablets (Novartis Pharmaceuticals UK Ltd) 56 tablet 4 x 14 tablets	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 10mg tablets (Novartis Pharmaceuticals UK Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 15mg tablets (Novartis Pharmaceuticals UK Ltd) 56 tablet 4 x 14 tablets	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 20mg tablets (Novartis Pharmaceuticals UK Ltd) 56 tablet 4 x 14 tablets	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 20mg tablets (Novartis Pharmaceuticals UK Ltd)	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 5mg tablets (Novartis Pharmaceuticals UK Ltd)	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 15mg tablets	Has basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 20mg tablets	Has basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 15mg tablets (Novartis Pharmaceuticals UK Ltd)	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 5mg tablets 56 tablet	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 5mg tablets (Novartis Pharmaceuticals UK Ltd) 56 tablet 4 x 14 tablets	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 20mg tablets 56 tablet	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 15mg tablets 56 tablet	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 20mg tablets (Novartis Pharmaceuticals UK Ltd) 60 tablet	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 15mg tablets (Novartis Pharmaceuticals UK Ltd) 60 tablet	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 5mg tablets (Novartis Pharmaceuticals UK Ltd) 60 tablet	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 15mg tablets 60 tablet	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 5mg tablets 60 tablet	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 20mg tablets 60 tablet	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Product containing precisely ruxolitinib 5 milligram/1 each conventional release oral tablet	Has basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Ruxolitinib 10mg tablets 56 tablet	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Product containing precisely ruxolitinib 10 milligram/1 each conventional release oral tablet	Has basis of strength substance	False	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 10mg tablets (Novartis Pharmaceuticals UK Ltd) 56 tablet 4 x 14 tablets	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier
Jakavi 10mg tablets (Novartis Pharmaceuticals UK Ltd)	Has basis of strength substance	True	Ruxolitinib	Inferred relationship	Existential restriction modifier

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3006149011	Ruxolitinib	en	Synonym	Active	Entire term case insensitive	SNOMED CT core module
3006175010	Ruxolitinib (substance)	en	Fully specified name	Active	Entire term case insensitive	SNOMED CT core module