Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
pT2b: Tumor more than 2 cm, but not more than 5 cm, in greatest dimension, limited to dermis and greater than 2 mm in thickness, but not more than 6 mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
pT2c: Tumor more than 2 cm, but not more than 5 cm, in greatest dimension, invading the subcutis and/or greater than 6 mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
pT3: Tumor more than 5 cm in greatest dimension (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
pT3a: Tumor more than 5 cm in greatest dimension, limited to dermis or not more than 2 mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
pT3b: Tumor more than 5 cm in greatest dimension, limited to dermis and greater than 2 mm in thickness, but not more than 6 mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
pT3c: Tumor more than 5 cm in greatest dimension, invading the subcutis and/or greater than 6 mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
pT4: Tumor invades deep extradermal structures (i.e. cartilage, skeletal muscle, or bone) (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
pT4b: Tumor invades deep extradermal structures (i.e. cartilage, skeletal muscle, or bone) greater than 6mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
pT4a: Tumor invades deep extradermal structures (i.e. cartilage, skeletal muscle, or bone) not more than 6mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
Stage I: Tumor confined to gland, 5 cm or less (adrenal cortical carcinoma) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Stage II: Tumor confined to gland, greater than 5 cm (adrenal cortical carcinoma) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Stage III: Extraglandular extension of tumor without other organ involvement (adrenal cortical carcinoma) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Stage IV: Distant metastasis or extension into other organs (adrenal cortical carcinoma) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Raised tumor |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Flat tumor |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Unpigmented tumor |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Pigmented tumor |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Necrotic tumor |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Hemorrhagic tumor |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Tumor pigmentation, diffuse |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Tumor pigmentation, patchy/focal |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Tumor pigmentation indeterminate |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Tumor pigmentation cannot be determined |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Tumor ulceration absent |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Oropharynx TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1: Tumor 2 cm or less in greatest dimension (oropharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Upper aerodigestive tract TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT2: Tumor more than 2 cm but not more than 4 cm in greatest dimension (oropharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT3: Tumor more than 4 cm in greatest dimension (oropharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4a: Tumor invades the larynx, deep/extrinsic muscle of tongue, medial pterygoid muscle, hard palate, or mandible (oropharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4b: Tumor invades lateral pterygoid muscle, pterygoid plates, lateral nasopharynx, or skull base or encases carotid artery (oropharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Lip and oral cavity TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT2: Tumor more than 2 cm but not more than 4 cm in greatest dimension (lip and oral cavity) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1: Tumor 2 cm or less in greatest dimension (lip and oral cavity) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1: Tumor 2 cm or less in greatest dimension |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT3: Tumor more than 4 cm in greatest dimension (lip and oral cavity) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4a: Tumor invades through cortical bone, inferior alveolar nerve, floor of mouth, or skin of face, i.e., chin or nose (lip) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4a: Tumor invades through cortical bone, into deep (extrinsic) muscle of tongue (genioglossus, hyoglossus, palatoglossus, and styloglossus), maxillary sinus, or skin of face (oral cavity) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4b: Tumor involves masticator space, pterygoid plates, or skull base and/or encases internal carotid artery (lip and oral cavity) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Hypopharyngeal TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Nasopharynx TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1: Tumor confined to the nasopharynx (nasopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT2a: Tumor extends to the soft tissues of the oropharnyx and/or nasal cavity without parapharyngeal extension (nasopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT2: Tumor extends to the soft tissues (nasopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT2b: Tumor extends to the soft tissues of the oropharnyx and/or nasal cavity with parapharyngeal extension (nasopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT3: Tumor involves bony structures and/or paranasal sinuses (nasopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4: Tumor with intracranial extension, and/or involvement of cranial nerves, infratemporal fossa, hypopharynx, orbit, or masticator space (nasopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1: Tumor limited to one subsite of hypopharynx and 2 cm or less in greatest dimension (hypopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT2: Tumor invades more than one subsite of hypopharynx or an adjacent site, or measures more than 2 cm but not more than 4 cm in greatest diameter without fixation of hemilarynx (hypopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT3: Tumor measures more than 4 cm in greatest dimension or with fixation of hemilarynx (hypopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4a: Tumor invades thyroid/cricoid cartilage, hyoid bone, thyroid gland, esophagus or central compartment of soft tissue (hypopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4b: Tumor invades prevertebral fascia, encases carotid artery, or involves mediastinal structures (hypopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Supraglottis TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1: Tumor limited to one subsite of supraglottis with normal vocal cord mobility (larynx, supraglottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT2: Tumor invades mucosa of more than one adjacent subsite of supraglottis or glottis or region outside the supraglottis (e.g., mucosa of base of tongue, vallecula, medial wall of pyriform sinus) without fixation of the larynx |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT3: Tumor limited to the larynx with vocal cord fixation and/or invades any of the following: postcrocoid area, pre-epiglottic tissues, paraglottic space, and/or minor thyroid cartilage erosion (e.g., inner cortex) (larynx, supraglottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4a: Tumor invades through the thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of the neck including deep extrinsic muscle of the tongue, strap muscles, thyroid, or esophagus) (larynx, supraglottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4b: Tumor invades prevertebral space, encases carotid artery, or invades mediastinal structures (larynx, supraglottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Glottis TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1: Tumor limited to the vocal cord(s) (may involve anterior or posterior commissure) with normal mobility (larynx, glottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1a: Tumor limited to one vocal cord (may involve anterior or posterior commissure) with normal mobility (larynx, glottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1b: Tumor involves both vocal cords (may involve anterior or posterior commissure) with normal mobility (larynx, glottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT2: Tumor extends to the supraglottis AND/OR subglottis, AND/OR with impaired vocal cord mobility (larynx, glottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT3: Tumor limited to the larynx with vocal cord fixation, and/or invades the paraglottic space, and/or minor thyroid cartilage erosion (larynx, glottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4a: Tumor invades through thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of the neck including deep intrinsic muscle of the tongue, strap muscles, thyroid, or esophagus) (larynx, glottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4b: Tumor invades prevertebral space, encases carotid artery, or invades mediastinal structures (larynx, glottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Subglottis TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1: Tumor limited to the subglottis (larynx, subglottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT2: Tumor extends to vocal cord(s) with normal or impaired mobility (larynx, subglottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT3: Tumor limited to larynx with vocal cord fixation (larynx, subglottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4a: Tumor invades cricoid or thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of the neck including deep extrinsic muscle of the tongue, strap muscles, thyroid, or esophagus) (larynx, subglottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4b: Tumor invades prevertebral space, encases carotid artery, or invades mediastinal structures (larynx, subglottis) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Maxillary sinus TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1: Tumor limited to the maxillary sinus mucosa with no erosion or destruction of bone (maxillary sinus) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT2: Tumor causing bone erosion or destruction including extension into the hard palate and/or middle nasal meatus, except extension to posterior wall of maxillary sinus and pterygoid plates (maxillary sinus) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT3: Tumor invades any of the following: bone of the posterior wall of maxillary sinus, subcutaneous tissues, floor or medial wall of orbit, pterygoid fossa, ethmoid sinuses (maxillary sinus) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4a: Tumor invades anterior orbital contents, skin of cheek, pterygoid plates, infratemporal fossa, cribriform plate, sphenoid or frontal sinuses (maxillary sinus) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4b: Tumor invades any of the following: orbital apex, dura, brain, middle cranial fossa, cranial nerves other than maxillary division of trigeminal nerve, nasopharynx, or clivus (maxillary sinus) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Nasal cavity and ethmoid sinus TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1: Tumor restricted to any one subsite, with or without bony invasion (nasal cavity and ethmoid sinus) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT2: Tumor invading two subsites in a single region or extending to involve an adjacent region within the nasoethmoidal complex, with or without bony invasion (nasal cavity and ethmoid sinus) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT3: Tumor extends to invade the medial wall or floor of the orbit, maxillary sinus, palate, or cribriform plate (nasal cavity and ethmoid sinus) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4a: Tumor invades any of the following: anterior orbital contents, skin of nose or cheek, minimal extension to anterior cranial fossa, pterygoid plates, sphenoid or frontal sinuses (nasal cavity and ethmoid sinus) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4b: Tumor invades any of the following: orbital apex, dura, brain, middle cranial fossa, cranial nerves other than maxillary division of trigeminal nerve, nasopharynx, or clivus (nasal cavity and ethmoid sinus) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pN1: Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension (upper aerodigestive tract) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pN2a: Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension (upper aerodigestive tract) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pN2c: Metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension (upper aerodigestive tract) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pN2b: Metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension (upper aerodigestive tract) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pN3: Metastasis in a lymph node, more than 6 cm in greatest dimension (upper aerodigestive tract) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pN1: Unilateral metastasis in lymph node(s), 6 cm or less in greatest dimension, above the supraclavicular fossa (nasopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pN2: Bilateral metastasis in lymph node(s), 6 cm or less in greatest dimension, above the supraclavicular fossa (nasopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pN3: Metastasis in a lymph node(s), more than 6 cm in dimension, and/or to supraclavicular fossa (nasopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pN3a: Metastasis in a lymph node(s), more than 6 cm in dimension (nasopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pN3b: Metastasis in lymph node(s) residing wholly or in part in the supraclavicular fossa (nasopharynx) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Extra-capsular extension of nodal tumor absent |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Extra-capsular extension of nodal tumor present |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
Major salivary gland TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT1: Tumor 2 cm or less in greatest dimension without extraparenchymal extension (major salivary glands) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT2: Tumor more than 2 cm but not more than 4 cm in greatest dimension without extraparenchymal extension (major salivary glands) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT3: Tumor more than 4 cm and/or tumor having extraparenchymal extension (major salivary glands) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
pT4a: Tumor invades skin, mandible, ear canal, and/or facial nerve (major salivary glands) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|