| Inbound Relationships | Type | Active | Source | Characteristic | Refinability | Group | 
| Classical juvenile pityriasis rubra pilaris | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Circumscribed juvenile pityriasis rubra pilaris | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Atypical juvenile pityriasis rubra pilaris | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Keratoderma blennorrhagicum | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Hereditary benign acanthosis nigricans | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 4 | 
| Acquired plantar keratoderma | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Acquired keratoderma | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Hereditary benign acanthosis nigricans with insulin resistance | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 4 | 
| Pityriasis rubra (Hebra) | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Hereditary acantholytic dermatosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Darier disease | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Pityriasis rubra pilaris | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Nail dystrophy due to Darier's disease | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 4 | 
| Acquired palmoplantar keratosis | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Acquired keratosis pilaris | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Trichodysplasia spinulosa caused by Polyomavirus | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Classical adult pityriasis rubra pilaris | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Atypical adult pityriasis rubra pilaris | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Acquired disorder of keratinization | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Drug-induced ichthyosiform reaction | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Focal acral hyperkeratosis | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Acral Darier's disease | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Palmar pitting due to Darier disease | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Acrokeratosis verruciformis of Darier disease | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Flexural Darier's disease | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Hypertrophic Darier's disease | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Linear/nevoid/zosteriform Darier's disease | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Acquired ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 1 | 
| Acrokeratosis paraneoplastica of Bazex | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Leukoencephalopathy, palmoplantar keratoderma syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 1 | 
| Hypohidrosis, enamel hypoplasia, palmoplantar keratoderma, intellectual disability syndrome | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 1 | 
| Corneal intraepithelial dyskeratosis, palmoplantar hyperkeratosis, laryngeal dyskeratosis syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 1 | 
| Leukokeratosis of skin | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Leukokeratosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 1 | 
| Diffuse palmoplantar keratoderma with painful fissures | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Skin fragility, wooly hair, palmoplantar keratoderma syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 4 | 
| Focal palmoplantar keratoderma with joint keratoses | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Ichthyosis hystrix | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Severe ichthyoses | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Ichthyosis, oral and digital anomalies syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 4 | 
| Atypical ichthyosis vulgaris with hypogonadism | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Congenital ichthyosis with hypotrichosis syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Autosomal recessive ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Acral self-healing collodion baby | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Keratitis ichthyosis and deafness syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Syndromic recessive X-linked ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Autosomal recessive exfoliative ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Ichthyosis linearis circumflexa | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Ichthyosis hystrix gravior of Rheydt | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Congenital non bullous ichthyosiform erythroderma | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Neonatal sclerosing cholangitis, ichthyosis, hypotrichosis syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 4 | 
| Cutaneous syndrome with ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Bathing suit ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Limb reduction-ichthyosis syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Autosomal recessive keratitis-ichthyosis-deafness syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Hystrix ichthyosis with deafness | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Ichthyosis, cerebellar degeneration and hepatosplenomegaly | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Ichthyosis bullosa of Siemens | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Non-bullous ichthyosiform erythroderma | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Sjögren-Larsson syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Erythrodermic lamellar ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Ichthyosis cheek eyebrow syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Congenital cataract ichthyosis syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Ichthyosis vulgaris | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Ichthyosis, alopecia, eclabion, ectropion, intellectual disability syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 4 | 
| X-linked intellectual disability, hypogonadism, ichthyosis, obesity, short stature syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Congenital ichthyosis of skin | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Sclerosing dysplasia of bone, ichthyosis, premature ovarian failure syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 4 | 
| Autosomal dominant ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Annular epidermolytic ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Lamellar ichthyosis (limited type) | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Senter syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Ichthyosis hystrix of Curth-Macklin | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Ichthyosis | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Porcupine man | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Lamellar ichthyosis AND trichorrhexis invaginata syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Keratinopathic ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Autosomal dominant ichthyosis vulgaris | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| X-linked ichthyosis with steryl-sulfatase deficiency | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Localized bullous ichthyosiform erythroderma | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Ichthyosis prematurity syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Autosomal dominant lamellar ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Ichthyosis follicularis with alopecia and photophobia | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Self-healing collodion baby | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Lamellar ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Ichthyosis, intellectual disability, dwarfism, renal impairment syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 4 | 
| Ichthyosis congenita with biliary atresia | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Non-erythrodermic lamellar ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Multiple sclerosis, ichthyosis, factor VIII deficiency syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 4 | 
| Ichthyosis, short stature, brachydactyly, microspherophakia syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 5 | 
| Palmoplantar keratoderma, spastic paralysis syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Harlequin ichthyosis | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 4 | 
| Netherton's syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Hypotrichosis and deafness syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Ichthyosis hystrix Bäfverstedt type | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Bullous ichthyosiform erythroderma | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Autosomal dominant focal non-epidermolytic palmoplantar keratoderma with plantar blistering | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 2 | 
| Rud's syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Hyperkeratotic eczema of palms and soles | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 5 | 
| Hyperkeratotic eczema of soles | Interprets | False | Keratinization, function | Inferred relationship | Existential restriction modifier | 3 | 
| Neu-Laxova syndrome | Interprets | True | Keratinization, function | Inferred relationship | Existential restriction modifier | 4 |