372536007: Topotecan (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Substance with enzyme inhibitor mechanism of action\Substance with topoisomerase inhibitor mechanism of action\Topotecan

\Drug or medicament\Antineoplastic agent\Topotecan

\Substance categorized by structure\Chemical\Chemical categorized by structure\Organic compound\Organic cyclic compound\Heterocyclic compound\Alkaloid\Topotecan

Status: current, Not sufficiently defined by necessary conditions definition status. Date: 31-Jul 2002. Module: SNOMED CT core module

Descriptions:

Id Description Lang Type Status Case? Module

1197829012 Topotecan (substance) en Fully specified name Active Entire term case insensitive SNOMED CT core module

1211069010 Topotecan en Synonym Active Entire term case insensitive SNOMED CT core module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Topotecan	Is a	Substance with topoisomerase inhibitor mechanism of action	true	Inferred relationship	Existential restriction modifier
Topotecan	Is a	Allergen class	false	Inferred relationship	Existential restriction modifier
Topotecan	Is a	Drug allergen	false	Inferred relationship	Existential restriction modifier
Topotecan	Has disposition	Topoisomerase inhibitor	true	Inferred relationship	Existential restriction modifier
Topotecan	Is a	Chemical categorized functionally	false	Inferred relationship	Existential restriction modifier
Topotecan	Is a	Substance with enzyme inhibitor mechanism of action	false	Inferred relationship	Existential restriction modifier
Topotecan	Is a	Antineoplastic agent	true	Inferred relationship	Existential restriction modifier
Topotecan	Is a	Alkaloid	true	Inferred relationship	Existential restriction modifier

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Topotecan hydrochloride	Is a	False	Topotecan	Inferred relationship	Existential restriction modifier
Product containing topotecan	Has active ingredient	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan (as topotecan hydrochloride) 4 milligram/1 vial powder for conventional release solution for injection	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg powder for infusion solution vial	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Product containing precisely topotecan (as topotecan hydrochloride) 1 milligram/1 vial powder for conventional release solution for injection	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Product containing topotecan in parenteral dose form (medicinal product form)	Has active ingredient	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing topotecan in oral dose form (medicinal product form)	Has active ingredient	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan chlorohydrate	Is a	False	Topotecan	Inferred relationship	Existential restriction modifier
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	Has basis of strength substance	False	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	Has basis of strength substance	False	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	Has precise active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	Has precise active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan (as topotecan hydrochloride) 4 milligram/1 vial powder for conventional release solution for injection	Has basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan (as topotecan hydrochloride) 1 milligram/1 vial powder for conventional release solution for injection	Has basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Topotecan hydrochloride	Is modification of	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan	Has active ingredient	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing only topotecan in oral dose form (medicinal product form)	Has active ingredient	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing only topotecan in parenteral dose form (medicinal product form)	Has active ingredient	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan (as topotecan hydrochloride) 1 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan (as topotecan hydrochloride) 250 microgram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan (as topotecan hydrochloride) 1 milligram/1 vial powder for conventional release solution for infusion (clinical drug)	Has basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan (as topotecan hydrochloride) 1 milligram/1 vial powder for conventional release solution for infusion and/or injection (clinical drug)	Has basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan (as topotecan hydrochloride) 4 milligram/1 vial powder for conventional release solution for infusion and/or injection (clinical drug)	Has basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan (as topotecan hydrochloride) 4 milligram/1 vial powder for conventional release solution for infusion (clinical drug)	Has basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier	1
Product containing precisely topotecan (as topotecan hydrochloride) 4 milligram/1 vial powder for conventional release solution for injection	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg i-v infusion (pdr for recon) - product	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg i-v infusion (pdr for recon) - product	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 4mg i-v infusion (pdr for recon)	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 1mg i-v infusion (pdr for recon)	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Product containing precisely topotecan (as topotecan hydrochloride) 1 milligram/1 vial powder for conventional release solution for injection	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg capsules	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg capsules	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 250microgram capsules	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 250microgram capsules	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 4mg powder for solution for injection vials (GlaxoSmithKline)	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 1mg powder for solution for injection vials (SmithKline Beecham Pharmaceuticals)	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg powder for solution for injection vials 1 vial	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg powder for solution for injection vials 1 vial	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 4mg powder for solution for injection vials (GlaxoSmithKline) 1 vial	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 1mg powder for solution for injection vials (SmithKline Beecham Pharmaceuticals) 1 vial	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 0.25mg capsules (GlaxoSmithKline)	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 1mg capsules (GlaxoSmithKline)	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg capsules 10 capsule	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 250microgram capsules 10 capsule	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 1mg capsules (GlaxoSmithKline) 10 capsule	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 0.25mg capsules (GlaxoSmithKline) 10 capsule	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 1mg powder for solution for injection vials (SmithKline Beecham Pharmaceuticals)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Product containing precisely topotecan (as topotecan hydrochloride) 1 milligram/1 vial powder for conventional release solution for injection	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 1mg powder for solution for injection vials (SmithKline Beecham Pharmaceuticals) 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg powder for solution for injection vials 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 1mg capsules (GlaxoSmithKline) 10 capsule	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 1mg capsules (GlaxoSmithKline)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg capsules 10 capsule	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 0.25mg capsules (GlaxoSmithKline)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 0.25mg capsules (GlaxoSmithKline) 10 capsule	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 250microgram capsules 10 capsule	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	False	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 4mg powder for solution for injection vials (GlaxoSmithKline) 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Hycamtin 4mg powder for solution for injection vials (GlaxoSmithKline)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Product containing precisely topotecan (as topotecan hydrochloride) 4 milligram/1 vial powder for conventional release solution for injection	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg powder for solution for injection vials 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg/4ml solution for infusion vials	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg/4ml solution for infusion vials	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg/4ml concentrate for solution for infusion vials (Hospira UK Ltd)	Has active ingredient	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg/4ml concentrate for solution for infusion vials (Hospira UK Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg/4ml solution for infusion vials 5 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg/4ml concentrate for solution for infusion vials (Hospira UK Ltd) 5 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg powder for solution for infusion vials (Actavis UK Ltd)	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg powder for solution for infusion vials (Actavis UK Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg powder for solution for infusion vials (Actavis UK Ltd)	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg powder for solution for infusion vials (Actavis UK Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg powder for solution for infusion vials (A A H Pharmaceuticals Ltd)	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg powder for solution for infusion vials (A A H Pharmaceuticals Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg powder for solution for infusion vials (A A H Pharmaceuticals Ltd)	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg powder for solution for infusion vials (A A H Pharmaceuticals Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg powder for solution for infusion vials (Actavis UK Ltd) 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg powder for solution for infusion vials (Actavis UK Ltd) 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg powder for solution for infusion vials (A A H Pharmaceuticals Ltd) 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg powder for solution for infusion vials (A A H Pharmaceuticals Ltd) 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg/1ml solution for infusion vials	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg/1ml solution for infusion vials	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg/1ml concentrate for solution for infusion vials (Accord Healthcare Ltd)	Has active ingredient	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg/1ml concentrate for solution for infusion vials (Accord Healthcare Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg powder for solution for infusion vials (Accord Healthcare Ltd)	Has active ingredient	False	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg powder for solution for infusion vials (Accord Healthcare Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg/4ml concentrate for solution for infusion vials (Accord Healthcare Ltd)	Has active ingredient	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg/4ml concentrate for solution for infusion vials (Accord Healthcare Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg/4ml solution for infusion vials 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg/1ml solution for infusion vials 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 1mg/1ml concentrate for solution for infusion vials (Accord Healthcare Ltd) 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg powder for solution for infusion vials (Accord Healthcare Ltd) 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg/4ml concentrate for solution for infusion vials (Accord Healthcare Ltd) 1 vial	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg/4ml concentrate for solution for infusion vials (Teva UK Ltd)	Has active ingredient	True	Topotecan	Inferred relationship	Existential restriction modifier
Topotecan 4mg/4ml concentrate for solution for infusion vials (Teva UK Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Topotecan	Inferred relationship	Existential restriction modifier

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Id	Description	Lang	Type	Status	Case?	Module
1197829012	Topotecan (substance)	en	Fully specified name	Active	Entire term case insensitive	SNOMED CT core module
1211069010	Topotecan	en	Synonym	Active	Entire term case insensitive	SNOMED CT core module