Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Kongenitte trommestikfingre/-tæer |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
2 |
Finger clubbing |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
1 |
Clubbing of nail |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
1 |
Clubbing of toes |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
1 |
Clubbing of toes |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
1 |
A form of primary hypertrophic osteoarthropathy, a rare hereditary disorder with characteristics of digital clubbing, pachydermia and subperiosteal new bone formation associated with pain, polyarthritis, cutis verticis gyrata, seborrhoea and hyperhidrosis. Three forms have been described: a complete form with pachydermia and periostitis, an incomplete form with evidence of bone abnormalities but lacking pachydermia, and a forme frusta with prominent pachydermia and minimal-to-absent skeletal changes. The disease typically begins during childhood or adolescence and may stabilise after 5-20 years of progression, or progress constantly. Mutations in the HPGD gene (4q33-q34) have been identified. The gene encodes 15-hydroxyprostaglandin dehydrogenase (15-PGDH), the main enzyme of prostaglandin degradation. Inherited as an autosomal recessive trait. |
Associated morphology |
True |
Clubbing |
Inferred relationship |
Some |
1 |
Clubbing of toes |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
1 |
Clubbing of toes |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
1 |
Clubbing of toes |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
2 |
Clubbing of nails associated with systemic disorder (disorder) |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
1 |
Clubbing of toes |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
1 |
Clubbing of toes |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
2 |
objektivt: trommestikfingre |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
1 |
Congenital clubnail |
Associated morphology |
True |
Clubbing |
Inferred relationship |
Some |
1 |
Kongenitte trommestikfingre/-tæer |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
2 |
objektivt: trommestikfingre |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
1 |
A form of primary hypertrophic osteoarthropathy, a rare hereditary disorder with characteristics of digital clubbing, pachydermia and subperiosteal new bone formation associated with pain, polyarthritis, cutis verticis gyrata, seborrhoea and hyperhidrosis. Three forms have been described: a complete form with pachydermia and periostitis, an incomplete form with evidence of bone abnormalities but lacking pachydermia, and a forme frusta with prominent pachydermia and minimal-to-absent skeletal changes. The disease typically begins during childhood or adolescence and may stabilise after 5-20 years of progression, or progress constantly. Mutations in the HPGD gene (4q33-q34) have been identified. The gene encodes 15-hydroxyprostaglandin dehydrogenase (15-PGDH), the main enzyme of prostaglandin degradation. Inherited as an autosomal recessive trait. |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
1 |
Clubbing of nails associated with systemic disorder (disorder) |
Associated morphology |
True |
Clubbing |
Inferred relationship |
Some |
1 |
Clubbing of nail |
Associated morphology |
True |
Clubbing |
Inferred relationship |
Some |
1 |
Clubbing of toes |
Associated morphology |
True |
Clubbing |
Inferred relationship |
Some |
1 |
Finger clubbing |
Associated morphology |
True |
Clubbing |
Inferred relationship |
Some |
1 |
Kongenitte trommestikfingre/-tæer |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
5 |
Congenital club finger (disorder) |
Associated morphology |
False |
Clubbing |
Inferred relationship |
Some |
3 |
Congenital club finger (disorder) |
Associated morphology |
True |
Clubbing |
Inferred relationship |
Some |
1 |
Hereditary clubbing |
Associated morphology |
True |
Clubbing |
Inferred relationship |
Some |
2 |