900000000000526001: REPLACED BY association reference set (foundation metadata concept)

SNOMED CT Concept\SNOMED CT Model Component\Foundation metadata concept (foundation metadata concept)\Reference set\Association type\Historical association reference set (foundation metadata concept)\REPLACED BY association reference set (foundation metadata concept)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT model component module (core metadata concept)

Descriptions:

Id Description Lang Type Status Case? Module

900000000001156010 REPLACED BY association reference set (foundation metadata concept) en Fully specified name Active Entire term case sensitive (core metadata concept) SNOMED CT model component module (core metadata concept)

900000000001157018 REPLACED BY association reference set en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT model component module (core metadata concept)

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
REPLACED BY association reference set (foundation metadata concept)	Is a	Historical association reference set (foundation metadata concept)	true	Inferred relationship	Some

Members	targetComponentId
T2: Urinary bladder tumor invades muscle	cT2
T2:Lung tumor with any of these features:>3cm in greatest dimension, involves main bronchus >2cm distal to carina;invades visceral pleura;assoc with atelectasis/obstructive pneumonitis extends to hilar region, does not involve entire lung	cT2
T2a (IIA): Endometrial tumor with endocervical glandular involvement	cT2a
T2a (IIA): Fallopian tube tumor with extension and/or metastasis to the uterus and/or ovaries	cT2a
T2a (IIA): Ovarian tumor with extension and/or implants on uterus and/or tube(s)	cT2a
T2a (IIA): Tumor of uterine cervix, T2 without parametrial invasion	cT2a
T2a: Aerodigestive tract tumor without parapharyngeal extension	cT2a
T2a: Prostate tumor involves one lobe	cT2a
T2a: Stomach tumor invades muscularis propria	cT2a
T2a: Urinary bladder tumor invades superficial muscle (inner half)	cT2a
T2b (IIB): Endometrial tumor with cervical stromal invasion	American Joint Committee on Cancer cT2b (qualifier value)
T2b (IIB): Fallopian tube/ovarian tumor with extension to other pelvic structures	American Joint Committee on Cancer cT2b (qualifier value)
T2b (IIB): Tumor of uterine cervix, T2 with parametrial invasion	American Joint Committee on Cancer cT2b (qualifier value)
T2b: Aerodigestive tract tumor with parapharyngeal extension	American Joint Committee on Cancer cT2b (qualifier value)
T2b: Stomach tumor invades subserosa	American Joint Committee on Cancer cT2b (qualifier value)
T2b: Urinary bladder tumor invades deep muscle (outer half)	American Joint Committee on Cancer cT2b (qualifier value)
T2c (IIC): Fallopian tube/ovarian tumor with pelvic extension (T2a or b) with malignant cells in ascites or peritoneal washings	American Joint Committee on Cancer cT2c (qualifier value)
T3 (III): Endometrial tumor with local and/or regional spread as specified in T3a, b, N1 and FIGO IIIA, B, and C below or adnexa (direct extension or metastasis) and/or cancer cells in ascites or peritoneal washings	American Joint Committee on Cancer cT3 (qualifier value)
T3 (III): Tumor of uterine cervix extends to the pelvic wall and/or involves the lower third of the vagina and/or causes hydronephrosis or nonfunctioning kidney	American Joint Committee on Cancer cT3 (qualifier value)
T3 (III): Vaginal tumor extends to pelvic wall	American Joint Committee on Cancer cT3 (qualifier value)
T3 category	American Joint Committee on Cancer cT3 (qualifier value)
T3: Aerodigestive tract tumor > 4 cm in greatest dimension	American Joint Committee on Cancer cT3 (qualifier value)
T3: Aerodigestive tract tumor extends to anterior orbit and/or maxillary sinus	American Joint Committee on Cancer cT3 (qualifier value)
T3: Aerodigestive tract tumor having extraparenchymal extension without seventh nerve involvement, and/or > 4 cm but < 6 cm in greatest dimension	American Joint Committee on Cancer cT3 (qualifier value)
T3: Aerodigestive tract tumor invades any of the following: bone of posterior wall of maxillary sinus, subcutaneous tissues, skin of cheek, floor or medial wall of orbit, infratemporal fossa, pterygoid plates, ethmoid sinuses	American Joint Committee on Cancer cT3 (qualifier value)
T3: Aerodigestive tract tumor limited to larynx with vocal cord fixation	American Joint Committee on Cancer cT3 (qualifier value)
T3: Aerodigestive tract tumor limited to larynx with vocal cord fixation and/or invades any of the following: postcricoid area, pre-epiglottic tissues, deep base of tongue	American Joint Committee on Cancer cT3 (qualifier value)
T3: Aerodigestive tract tumor measures > 4 cm in greatest dimension, or with fixation of hemilarynx	American Joint Committee on Cancer cT3 (qualifier value)
T3: Aerodigestive tumor invades bony structures and/or paranasal sinuses	American Joint Committee on Cancer cT3 (qualifier value)
T3: Ampulla tumor invades 2 cm or less into pancreas	American Joint Committee on Cancer cT3 (qualifier value)
T3: Breast tumor >5 cm in greatest dimension	American Joint Committee on Cancer cT3 (qualifier value)
T3: Colon/rectum tumor invades through the muscularis propria into the subserosa or the nonperitonealized pericolic or perirectal soft tissues	American Joint Committee on Cancer cT3 (qualifier value)
T3: Esophageal tumor invades adventitia	American Joint Committee on Cancer cT3 (qualifier value)
T3: Lung tumor of any size associated atelectasis or obstructive pneumonitis of the entire lung	American Joint Committee on Cancer cT3 (qualifier value)
T3: Lung tumor of any size in the main bronchus < 2 cm distal to the carina but without involvement of the carina	American Joint Committee on Cancer cT3 (qualifier value)
T3: Lung tumor of any size that directly invades any of the following: chest wall (including superior sulcus tumors); diaphragm; mediastinal pleura; parietal pericardium	American Joint Committee on Cancer cT3 (qualifier value)
T3: Pancreatic tumor extends directly to any of the following: duodenum; bile duct; peripancreatic tissues	American Joint Committee on Cancer cT3 (qualifier value)
T3: Pleural tumor invades any of the following: ipsilateral chest wall muscle, ribs, or media-stinal organs or tissues	American Joint Committee on Cancer cT3 (qualifier value)
T3: Prostate tumor extends through the prostatic capsule	American Joint Committee on Cancer cT3 (qualifier value)
T3: Renal pelvis tumor invades beyond muscularis peripelvic fat or the renal parenchyma	American Joint Committee on Cancer cT3 (qualifier value)
T3: Renal tumor extends into major veins or invades the adrenal gland or perinephric tissues but not beyond Gerota's fascia	American Joint Committee on Cancer cT3 (qualifier value)
T3: Stomach tumor penetrates serosa without invasion of adjacent structures	American Joint Committee on Cancer cT3 (qualifier value)
T3: Testicular tumor invades spermatic cord with or without vascular/lymphatic invasion	American Joint Committee on Cancer cT3 (qualifier value)
T3: Thyroid tumor > 4 cm, limited to thyroid	American Joint Committee on Cancer cT3 (qualifier value)
T3: Ureteral tumor invades beyond muscularis into periureteric fat	American Joint Committee on Cancer cT3 (qualifier value)
T3: Urinary bladder tumor invades perivesical tissue	American Joint Committee on Cancer cT3 (qualifier value)
T3a (IIIA): Fallopian tube/ovarian tumor with microscopic peritoneal metastasis beyond pelvis	American Joint Committee on Cancer cT3a (qualifier value)
T3a (IIIA): Tumor of uterine cervix involves lower third of vagina, but not pelvic wall	American Joint Committee on Cancer cT3a (qualifier value)
T3a: Bladder tumor invades perivesical tissue microscopically	American Joint Committee on Cancer cT3a (qualifier value)
T3a: Prostate tumor with extracapsular extension (unilateral or bilateral)	American Joint Committee on Cancer cT3a (qualifier value)
T3a: Renal tumor invades the adrenal gland or perinephric tissues but not beyond Gerota's fascia	American Joint Committee on Cancer cT3a (qualifier value)
T3b (IIIB): Endometrial tumor with vaginal involvement (direct extension or metastasis)	cT3b
T3b (IIIB): Fallopian tube/ovarian tumor with macroscopic peritoneal metastasis beyond pelvis < 2 cm in greatest dimension	cT3b
T3b (IIIB): Tumor of uterine cervix extends to pelvic wall and/or causes hydronephrosis or nonfunctioning kidney	cT3b
T3b: Bladder tumor invades perivesical tissue macroscopically (extravesicular mass)	cT3b
T3b: Prostate tumor invades the seminal vesicle(s)	cT3b
T3b: Renal tumor grossly extends into the renal vein(s) or vena cava below the diaphragm	cT3b
T3c (IIIC): Fallopian tube/ovarian tumor with peritoneal metastasis beyond pelvis > 2 cm in greatest dimension and/or regional lymph node metastasis	American Joint Committee on Cancer cT3c (qualifier value)
T3c: Renal tumor grossly extends into the vena cava above the diaphragm	American Joint Committee on Cancer cT3c (qualifier value)
T4 (IVA): Endometrial tumor invades bladder mucosa and/or bowel mucosa	cT4
T4 (IVA): Tumor of uterine cervix/vagina invades mucosa of bladder or rectum and/or extends beyond true pelvis	cT4
T4 category	cT4
T4: Aerodigestive tract tumor invades adjacent structures (pterygoid muscles, mandible, hard palate, deep muscle of tongue, larynx)	cT4
T4: Aerodigestive tract tumor invades adjacent structures (thyroid/cricoid cartilage, carotid artery, soft tissues of neck, prevertebral fascia/muscles, thyroid and/or esophagus)	cT4
T4: Aerodigestive tract tumor invades orbital contents beyond the floor or medial wall including apex and/or any of the following: cribriform plate, base of skull, nasopharynx, sphenoid sinus, frontal sinus	cT4
T4: Aerodigestive tract tumor with intracranial extension and/or involvement of cranial nerves, infratemporal fossa, hypopharynx or orbit	cT4
T4: Aerodigestive tract tumor with intracranial extension, orbital extension including apex, involving sphenoid and/or frontal sinus and/or skin of nose	cT4
T4: Aerodigestive tumor invades base of skull, seventh nerve, and/or exceeds 6 cm in greatest dimension	cT4
T4: Ampulla tumor invades >2 cm into pancreas and/or into other adjacent organs	cT4
T4: Breast tumor of any size with direct extension to chest wall or skin	cT4
T4: Lip: Tumor invades adjacent structures (cortical bone, inferior alveolar nerve, floor of mouth, skin of face)	cT4
T4: Lung tumor of any size that invades any of the following: mediastinum; heart; great vessels; trachea; esophagus; vertebral body; carina	cT4
T4: Lung tumor of any size with a malignant pleural effusion	cT4
T4: Lung tumor of any size with separate tumor nodule(s) in same lobe	cT4
T4: Oral Cavity: Tumor invades adjacent structures (cortical bone, deep (extrinsic) muscle of tongue, maxillary sinus, skin)	cT4
T4: Pancreas tumor extends directly to any of the following: stomach; spleen; colon; adjacent large vessels	cT4
T4: Pleural tumor directly extends to any of the following: contralateral pleura, contralateral lung, peritoneum, intra-abdominal organs, cervical tissues	cT4
T4: Renal pelvis/ureter tumor invades adjacent organs, or through the kidney into the perinephric fat	cT4
T4: Renal tumor invades beyond Gerota's fascia	cT4
T4: Testicular tumor invades scrotum with or without vascular/lymphatic invasion	cT4
T4: Thyroid tumor of any size extending beyond the thyroid capsule	cT4
T4: Tumor directly invades adjacent structures	cT4
T4: Tumor invades through cricoid or thyroid cartilage and/or extends into other tissues beyond the larynx (trachea, soft tissues of neck, thyroid, esophagus)	cT4
T4: Tumor invades through thyroid cartilage and/or extends to other tissues beyond the larynx (trachea, soft tissues of neck, pharynx)	cT4
T4: Tumor invades through thyroid cartilage, and/or extends into soft tissues of the neck, thyroid, and/or esophagus	cT4
T4: Urinary bladder tumor invades any of the following: prostate, uterus, vagina, pelvic wall abdominal wall	cT4
T4a: Bladder tumor invades prostate or uterus or vagina	American Joint Committee on Cancer cT4a (qualifier value)
T4a: Breast tumor with extension to chest wall	American Joint Committee on Cancer cT4a (qualifier value)
T4a: Colon/rectum tumor directly invades other organs or structures	American Joint Committee on Cancer cT4a (qualifier value)
T4b: Bladder tumor invades pelvic wall or abdominal wall	cT4b
T4b: Colon/rectum tumor penetrates the visceral peritoneum	cT4b
T4b: Edema (including peau d'orange) or ulceration of the skin of the breast or satellite skin nodules confined to the same breast	cT4b
T4c: Breast tumor, both T4a and T4b	American Joint Committee on Cancer cT4c (qualifier value)
T4d: Inflammatory carcinoma (breast)	American Joint Committee on Cancer cT4d (qualifier value)
T4d: Inflammatory carcinoma of breast with involvement of skin and chest wall by carcinoma	American Joint Committee on Cancer cT4d (qualifier value)
TNM tumour staging	American Joint Committee on Cancer allowable value
TNM tumour staging	American Joint Committee on Cancer allowable value
TX category	American Joint Committee on Cancer cTX (qualifier value)
Ta: Noninvasive papillary carcinoma (urinary tract)	American Joint Committee on Cancer cTa (qualifier value)
Tacrolimus 0.03% ointment	Product containing precisely tacrolimus 300 microgram/1 gram conventional release cutaneous ointment (clinical drug)
Tacrolimus 0.1% ointment	Product containing precisely tacrolimus 1 milligram/1 gram conventional release cutaneous ointment (clinical drug)

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Reference Sets

Reference set descriptor

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Id	Description	Lang	Type	Status	Case?	Module
900000000001156010	REPLACED BY association reference set (foundation metadata concept)	en	Fully specified name	Active	Entire term case sensitive (core metadata concept)	SNOMED CT model component module (core metadata concept)
900000000001157018	REPLACED BY association reference set	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT model component module (core metadata concept)