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96058005: Cilastatin (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Hydrolase inhibitor\Peptide hydrolase inhibitor\Cilastatin

\Drug or medicament (substance)\Cilastatin

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Sulfur and/or sulfur compound\Sulfur compound\Organic sulfur compound\Mercaptan compound\Organic sulfide compound\Cilastatin

\Organic compound\Organic sulfur compound\Mercaptan compound\Organic sulfide compound\Cilastatin

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Cilastatin	Is a	Beta-lactam antibacterial agent	false	Inferred relationship	Some
Cilastatin	Is a	Fatty acid (substance)	false	Inferred relationship	Some
Cilastatin	Is a	Drug allergen	false	Inferred relationship	Some
Cilastatin	Is a	Peptide hydrolase inhibitor	true	Inferred relationship	Some
Cilastatin	Has disposition (attribute)	Peptide hydrolase inhibitor (disposition)	true	Inferred relationship	Some
Cilastatin	Is a	Chemical categorized functionally	false	Inferred relationship	Some
Cilastatin	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Cilastatin	Is a	Organic sulfide compound	true	Inferred relationship	Some
Cilastatin	Is a	Drug or medicament (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing cilastatin and imipenem (medicinal product)	Has active ingredient	True	Cilastatin	Inferred relationship	Some	2
Imipenem 500mg/cilastatin 500mg powder for infusion solution vial	Has active ingredient	False	Cilastatin	Inferred relationship	Some
Product containing precisely cilastatin (as cilastatin sodium) 500 milligram and imipenem (as imipenem monohydrate) 500 milligram/1 vial powder for conventional release suspension for injection	Has active ingredient	False	Cilastatin	Inferred relationship	Some
Imipenem 500mg/cilastatin 500mg powder for infusion solution transfer vial	Has active ingredient	False	Cilastatin	Inferred relationship	Some
Cilastatin (as cilastatin sodium) 250 mg and imipenem anhydrous (as imipenem) 250 mg powder for solution for injection vial	Has active ingredient	False	Cilastatin	Inferred relationship	Some
Imipenem 750mg/cilastatin 750mg powder for injection solution vial	Has active ingredient	False	Cilastatin	Inferred relationship	Some
Product containing cilastatin (medicinal product)	Has active ingredient	True	Cilastatin	Inferred relationship	Some	1
Cilastatin- and imipenem-containing product in parenteral dose form	Has active ingredient	True	Cilastatin	Inferred relationship	Some	2
Cilastatin sodium (substance)	Is a	False	Cilastatin	Inferred relationship	Some
Product containing precisely cilastatin (as cilastatin sodium) 500 milligram and imipenem (as imipenem monohydrate) 500 milligram/1 vial powder for conventional release suspension for injection	Has basis of strength substance (attribute)	False	Cilastatin	Inferred relationship	Some	1
Cilastatin sodium (substance)	Is modification of (attribute)	True	Cilastatin	Inferred relationship	Some
Product containing only cilastatin (medicinal product)	Has active ingredient	True	Cilastatin	Inferred relationship	Some	1
Cilastatin and imipenem only product	Has active ingredient	True	Cilastatin	Inferred relationship	Some	2
Product containing only cilastatin and imipenem in parenteral dose form (medicinal product form)	Has active ingredient	True	Cilastatin	Inferred relationship	Some	2
Product containing precisely cilastatin (as cilastatin sodium) 500 milligram and imipenem anhydrous (as imipenem) 500 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Cilastatin	Inferred relationship	Some	2
Cilastatin (as cilastatin sodium) 250 mg and imipenem anhydrous (as imipenem) 250 mg powder for solution for injection vial	Has basis of strength substance (attribute)	True	Cilastatin	Inferred relationship	Some	2
Product containing cilastatin and imipenem and relebactam (medicinal product)	Has active ingredient	True	Cilastatin	Inferred relationship	Some	3
Product containing only cilastatin and imipenem and relebactam (medicinal product)	Has active ingredient	True	Cilastatin	Inferred relationship	Some	3
Product containing cilastatin and imipenem and relebactam in parenteral dose form (medicinal product form)	Has active ingredient	True	Cilastatin	Inferred relationship	Some	3
Cilastatin and imipenem and relebactam only product in parenteral dose form	Has active ingredient	True	Cilastatin	Inferred relationship	Some	3
Product containing precisely cilastatin (as cilastatin sodium) 500 milligram and imipenem 500 milligram/1 vial powder for conventional release suspension for injection (clinical drug)	Has basis of strength substance (attribute)	True	Cilastatin	Inferred relationship	Some	2
Product containing precisely cilastatin (as cilastatin sodium) 500 milligram and imipenem 500 milligram/1 vial powder for conventional release solution for infusion (clinical drug)	Has basis of strength substance (attribute)	True	Cilastatin	Inferred relationship	Some	2
Cilastatin (as cilastatin sodium) 500 mg and imipenem 500 mg and relebactam 250 mg powder for solution for infusion vial	Has basis of strength substance (attribute)	True	Cilastatin	Inferred relationship	Some	3

Reference Sets

Belgian subset for AllergyIntolerance, causative agent, drug

GB English

US English

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Id	Description	Lang	Type	Status	Case?	Module
159098019	Cilastatin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
840341010	Cilastatin (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
800761000172110	cilastatine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Belgian module (core metadata concept)
800771000172118	cilastatine	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Belgian module (core metadata concept)