735172002: Pemetrexed disodium (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Oxidoreductase inhibitor\Dihydrofolate reductase inhibitor\Pemetrexed disodium (substance)
\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Substance with phosphoribosylglycinamide formyltransferase inhibitor mechanism of action (substance)\Pemetrexed disodium (substance)
\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Methyltransferase inhibitor\Thymidylate synthase inhibitor\Pemetrexed disodium (substance)
\Substance categorized by disposition\Immunomodulator\Antimetabolite (substance)\Antifolate (substance)\Pemetrexed disodium (substance)

\Drug or medicament (substance)\Substance with phosphoribosylglycinamide formyltransferase inhibitor mechanism of action (substance)\Pemetrexed disodium (substance)
\Drug or medicament (substance)\Oxidoreductase inhibitor\Dihydrofolate reductase inhibitor\Pemetrexed disodium (substance)
\Drug or medicament (substance)\Immunologic agent (substance)\Antifolate (substance)\Pemetrexed disodium (substance)
\Drug or medicament (substance)\Antineoplastic agent (substance)\Antimetabolite (substance)\Antifolate (substance)\Pemetrexed disodium (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic acid and/or organic acid derivative\Carboxylic acid and/or carboxylic acid derivative (substance)\Carboxylic acid anion (substance)\...

\Amino acid anion (substance)\Alpha amino acid anion (substance)\Glutamate (substance)\Pemetrexed disodium (substance)

\Dicarboxylate\Glutamate (substance)\Pemetrexed disodium (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3513351012 Pemetrexed disodium (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3513352017 Pemetrexed disodium en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

831791000172117 pémétrexed disodique fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Belgian module (core metadata concept)

831801000172116 pemetrexeddinatrium nl Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Belgian module (core metadata concept)

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Pemetrexed disodium (substance)	Is a	Pemetrexed (substance)	false	Inferred relationship	Some
Pemetrexed disodium (substance)	Has disposition (attribute)	Antimetabolite (disposition)	true	Inferred relationship	Some
Pemetrexed disodium (substance)	Is a	Glutamate (substance)	true	Inferred relationship	Some
Pemetrexed disodium (substance)	Has disposition (attribute)	Dihydrofolate reductase inhibitor (disposition)	true	Inferred relationship	Some
Pemetrexed disodium (substance)	Is a	Antifolate (substance)	true	Inferred relationship	Some
Pemetrexed disodium (substance)	Is a	Substance with phosphoribosylglycinamide formyltransferase inhibitor mechanism of action (substance)	true	Inferred relationship	Some
Pemetrexed disodium (substance)	Is a	Thymidylate synthase inhibitor	true	Inferred relationship	Some
Pemetrexed disodium (substance)	Has disposition (attribute)	Thymidylate synthase inhibitor (disposition)	true	Inferred relationship	Some
Pemetrexed disodium (substance)	Is a	Dihydrofolate reductase inhibitor	true	Inferred relationship	Some
Pemetrexed disodium (substance)	Has disposition (attribute)	Phosphoribosylglycinamide formyltransferase inhibitor (disposition)	true	Inferred relationship	Some
Pemetrexed disodium (substance)	Is modification of (attribute)	Pemetrexed (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing precisely pemetrexed (as pemetrexed disodium) 100 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Pemetrexed disodium (substance)	Inferred relationship	Some	1
Product containing precisely pemetrexed (as pemetrexed disodium) 500 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Pemetrexed disodium (substance)	Inferred relationship	Some	1
Product containing precisely pemetrexed (as pemetrexed disodium) 100 milligram/1 vial powder for conventional release solution for infusion (clinical drug)	Has precise active ingredient	True	Pemetrexed disodium (substance)	Inferred relationship	Some	1
Pemetrexed (as pemetrexed disodium) 500 mg powder for solution for infusion vial	Has precise active ingredient	True	Pemetrexed disodium (substance)	Inferred relationship	Some	1

Reference Sets

Belgian subset for AllergyIntolerance, causative agent, drug