708711009: Trametinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Substance with B-Raf inhibitor mechanism of action (substance)\Trametinib (substance)

\Drug or medicament (substance)\Trametinib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\...

\Pyrimidine and/or pyrimidine derivative\Trametinib (substance)

\Amide and/or amide derivative (substance)\Amide\Acetamide and/or acetamide derivative\Acetamide (substance)\Trametinib (substance)

\Organic compound\Organic cyclic compound\Substance with cyclopropane structure (substance)\Trametinib (substance)
\Organic compound\Organic cyclic compound\Heterocyclic compound\Pyrimidine and/or pyrimidine derivative\Trametinib (substance)
\Organic compound\Organic nitrogen compound\Pyrimidine and/or pyrimidine derivative\Trametinib (substance)
\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Amide\Acetamide and/or acetamide derivative\Acetamide (substance)\Trametinib (substance)
\Organic compound\Hydrocarbon\Alkane\Cyclic alkane\Substance with cyclopropane structure (substance)\Trametinib (substance)

\Substance categorised by physical state\Gaseous substance\Alkane\Cyclic alkane\Substance with cyclopropane structure (substance)\Trametinib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2015. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3036029017 Trametinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core
3036340017 Trametinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
847041000172117 tramétinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Belgian module (core metadata concept)
847051000172115 trametinib nl Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Belgian module (core metadata concept)

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Trametinib (substance)	Is a	Substance with B-Raf inhibitor mechanism of action (substance)	true	Inferred relationship	Some
Trametinib (substance)	Is a	Cyclopropane	false	Inferred relationship	Some
Trametinib (substance)	Is a	Acetamide (substance)	true	Inferred relationship	Some
Trametinib (substance)	Is a	Pyrimidine and/or pyrimidine derivative	true	Inferred relationship	Some
Trametinib (substance)	Has disposition (attribute)	B-Raf inhibitor (disposition)	true	Inferred relationship	Some
Trametinib (substance)	Is a	Chemical categorized functionally	false	Inferred relationship	Some
Trametinib (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Trametinib (substance)	Is a	Substance with cyclopropane structure (substance)	true	Inferred relationship	Some
Trametinib (substance)	Is a	Drug or medicament (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing trametinib (medicinal product)	Has active ingredient	True	Trametinib (substance)	Inferred relationship	Some	1
Trametinib-containing product in oral dose form	Has active ingredient	True	Trametinib (substance)	Inferred relationship	Some	1
Trametinib dimethyl sulfoxide (substance)	Is a	False	Trametinib (substance)	Inferred relationship	Some
Trametinib dimethyl sulfoxide (substance)	Is modification of (attribute)	True	Trametinib (substance)	Inferred relationship	Some
Product containing only trametinib (medicinal product)	Has active ingredient	True	Trametinib (substance)	Inferred relationship	Some	1
Product containing only trametinib in oral dose form (medicinal product form)	Has active ingredient	True	Trametinib (substance)	Inferred relationship	Some	1
Trametinib (as trametinib dimethyl sulfoxide) 500 microgram oral tablet	Has basis of strength substance (attribute)	True	Trametinib (substance)	Inferred relationship	Some	1
Trametinib (as trametinib dimethyl sulfoxide) 2 mg oral tablet	Has basis of strength substance (attribute)	True	Trametinib (substance)	Inferred relationship	Some	1

Reference Sets

Belgian subset for AllergyIntolerance, causative agent, drug