387332007: Isosorbide dinitrate (substance)

SNOMED CT Concept\Substance\...

\Drug or medicament (substance)\Cardiovascular agent (substance)\Hypotensive agent (substance)\Vasodilator (substance)\Nitrate-based vasodilating agent (substance)\Isosorbide dinitrate (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\...

\Nitrate-based vasodilating agent (substance)\Isosorbide dinitrate (substance)

\Nitrous acid ester (substance)\Isosorbide dinitrate (substance)

\Organic compound\Organic cyclic compound\Isosorbide dinitrate (substance)
\Organic compound\Ester\Nitrous acid ester (substance)\Isosorbide dinitrate (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Isosorbide dinitrate (substance)	Is a	Isosorbide (substance)	false	Inferred relationship	Some
Isosorbide dinitrate (substance)	Is a	Nitrate-based vasodilating agent (substance)	true	Inferred relationship	Some
Isosorbide dinitrate (substance)	Is a	Nitrous acid ester (substance)	true	Inferred relationship	Some
Isosorbide dinitrate (substance)	Is modification of (attribute)	Isosorbide (substance)	false	Inferred relationship	Some
Isosorbide dinitrate (substance)	Is a	Organic cyclic compound	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Isosorbide dinitrate adverse reaction	Causative agent	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Parenteral isosorbide dinitrate adverse reaction	Causative agent	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Oral isosorbide dinitrate adverse reaction	Causative agent	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Modified release isosorbide dinitrate adverse reaction	Causative agent	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
allergie au dinitrate d'isosorbide	Causative agent	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Parenteral isosorbide dinitrate allergy	Causative agent	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Oral isosorbide dinitrate allergy	Causative agent	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Modified release isosorbide dinitrate allergy	Causative agent	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate overdose	Causative agent	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate [generic additions]	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 5mg sublingual tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 10 mg oral tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 20 mg oral tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 30 mg oral tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 20mg m/r tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 500micrograms/mL injection solution 50mL vial	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 1.25 mg/actuation sublingual spray	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 30mg transdermal spray	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 40mg m/r tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 1mg/mL injection solution 10mL ampule	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 1mg/mL injection solution 50mL vial	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Modified release isosorbide dinitrate	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing isosorbide dinitrate in parenteral dosage form	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing isosorbide dinitrate in oral dosage form	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Transdermal isosorbide dinitrate	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 5 mg oral tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing precisely isosorbide dinitrate 2.5 milligram/1 each conventional release sublingual tablet (clinical drug)	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 40 mg oral tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 40mg m/r capsule	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing isosorbide dinitrate (medicinal product)	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing hydralazine and isosorbide dinitrate (medicinal product)	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing precisely hydralazine 37.5 milligram and isosorbide dinitrate 20 milligram/1 each conventional release oral tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing precisely isosorbide dinitrate 10 milligram/1 each conventional release sublingual tablet (clinical drug)	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing isosorbide dinitrate in sublingual dosage form	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Isosorbide dinitrate 5 mg sublingual tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Product containing isosorbide dinitrate in oropharyngeal dosage form	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some
Oral isosorbide dinitrate allergy	Causative agent	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
allergie au dinitrate d'isosorbide	Causative agent	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Modified release isosorbide dinitrate allergy	Causative agent	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Parenteral isosorbide dinitrate allergy	Causative agent	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 10 mg oral tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 10 mg oral tablet	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 20 mg oral tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 20 mg oral tablet	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 30 mg oral tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 30 mg oral tablet	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 5 mg oral tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 5 mg oral tablet	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 40 mg oral tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 40 mg oral tablet	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely hydralazine 37.5 milligram and isosorbide dinitrate 20 milligram/1 each conventional release oral tablet	Has active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Product containing precisely hydralazine 37.5 milligram and isosorbide dinitrate 20 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Product containing precisely hydralazine 37.5 milligram and isosorbide dinitrate 20 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 20 milligram/1 each prolonged-release oral tablet (clinical drug)	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 20 milligram/1 each prolonged-release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 40 milligram/1 each prolonged-release oral capsule (clinical drug)	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 40 milligram/1 each prolonged-release oral capsule (clinical drug)	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 40 milligram/1 each prolonged-release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 40 milligram/1 each prolonged-release oral tablet (clinical drug)	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 30 mg oral tablet	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 10 mg oral tablet	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 20 mg oral tablet	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely hydralazine 37.5 milligram and isosorbide dinitrate 20 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 5 mg oral tablet	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 40 mg oral tablet	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 1.25 mg/actuation sublingual spray	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 1.25 mg/actuation sublingual spray	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 30 mg/actuation transdermal spray	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 30 mg/actuation transdermal spray	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 10 milligram/10 milliliter conventional release solution for injection ampule	Has basis of strength substance (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 10 milligram/10 milliliter conventional release solution for injection ampule	Has precise active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 50 milligram/50 milliliter conventional release solution for injection bottle	Has precise active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 50 milligram/50 milliliter conventional release solution for injection bottle	Has basis of strength substance (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 25 milligram/50 milliliter conventional release solution for injection bottle	Has precise active ingredient	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 25 milligram/50 milliliter conventional release solution for injection bottle	Has basis of strength substance (attribute)	False	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 500 microgram/1 milliliter conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 500 microgram/1 milliliter conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 1 mg/mL solution for injection	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 1 mg/mL solution for injection	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 10 milligram/1 each conventional release sublingual tablet (clinical drug)	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 10 milligram/1 each conventional release sublingual tablet (clinical drug)	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 5 mg sublingual tablet	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate 5 mg sublingual tablet	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 2.5 milligram/1 each conventional release sublingual tablet (clinical drug)	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing precisely isosorbide dinitrate 2.5 milligram/1 each conventional release sublingual tablet (clinical drug)	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Hydralazine hydrochloride 37.5 mg and isosorbide dinitrate 20 mg oral tablet	Has basis of strength substance (attribute)	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Hydralazine hydrochloride 37.5 mg and isosorbide dinitrate 20 mg oral tablet	Has precise active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Product containing only isosorbide dinitrate (medicinal product)	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing isosorbide dinitrate (medicinal product)	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Product containing hydralazine and isosorbide dinitrate (medicinal product)	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Product containing only hydralazine and isosorbide dinitrate (medicinal product)	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Hydralazine- and isosorbide dinitrate-containing product in oral dose form	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Product containing only hydralazine and isosorbide dinitrate in oral dose form (medicinal product form)	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	2
Isosorbide dinitrate only product in oral dose form	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate-containing product in oral dose form	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate-containing product in parenteral dose form	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate only product in parenteral dose form	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate-containing product in oromucosal dose form	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate only product in oromucosal dose form	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate-containing product in transdermal dose form	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1
Isosorbide dinitrate only product in transdermal dose form	Has active ingredient	True	Isosorbide dinitrate (substance)	Inferred relationship	Some	1

Reference Sets

Belgian subset for AllergyIntolerance, causative agent, drug

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Id	Description	Lang	Type	Status	Case?	Module
1461510013	Isosorbide dinitrate (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481431017	Isosorbide dinitrate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
819101000172116	dinitrate d'isosorbide	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Belgian module (core metadata concept)
1560741000172113	isosorbide dinitrate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Belgian module (core metadata concept)
819111000172118	isosorbidedinitraat	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Belgian module (core metadata concept)