386856007: Donepezil hydrochloride (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Acetylcholinesterase inhibitor\Centrally acting acetylcholinesterase inhibitor\Donepezil hydrochloride (substance)
\Substance categorized by disposition\Receptor agonist\Substance with sigma-1 receptor agonist mechanism of action (substance)\Donepezil hydrochloride (substance)

\Drug or medicament (substance)\Autonomic agent (substance)\Parasympathomimetic agent (substance)\Acetylcholinesterase inhibitor\Centrally acting acetylcholinesterase inhibitor\Donepezil hydrochloride (substance)
\Drug or medicament (substance)\Central nervous system agent (substance)\Donepezil hydrochloride (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative (substance)\Donepezil hydrochloride (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative (substance)\Donepezil hydrochloride (substance)
\Organic compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative (substance)\Donepezil hydrochloride (substance)
\Organic compound\Ketone\Cyclic ketone\Donepezil hydrochloride (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Donepezil hydrochloride (substance)	Is a	Donepezil (substance)	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	Has disposition (attribute)	Acetylcholine receptor agonist (disposition)	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	Has disposition (attribute)	Cholinesterase inhibitor	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	Has disposition (attribute)	Centrally acting acetylcholinesterase inhibitor (disposition)	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is modification of (attribute)	Donepezil (substance)	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Drug allergen	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Piperidine derivative (substance)	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Centrally acting acetylcholinesterase inhibitor	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Parasympathomimetic agent (substance)	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Chemical categorized functionally	false	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Substance with sigma-1 receptor agonist mechanism of action (substance)	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	Has disposition (attribute)	Sigma-1 receptor agonist (disposition)	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Cyclic ketone	true	Inferred relationship	Some
Donepezil hydrochloride (substance)	Is a	Central nervous system agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing donepezil hydrochloride	Has active ingredient	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil hydrochloride 5 mg oral tablet	Has active ingredient	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil hydrochloride 10 mg oral tablet	Has active ingredient	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil 1mg/mL oral solution	Has active ingredient	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil 5mg orally disintegrating tablet	Has active ingredient	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil 10mg orally disintegrating tablet	Has active ingredient	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Aricept odt 5mg orally disintegrating tablet	Has active ingredient	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil hydrochloride 23 mg oral tablet	Has active ingredient	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil hydrochloride 5 mg oral tablet	Has active ingredient	False	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 5 mg oral tablet	Has basis of strength substance (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 10 mg oral tablet	Has active ingredient	False	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 10 mg oral tablet	Has basis of strength substance (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 23 mg oral tablet	Has active ingredient	False	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 23 mg oral tablet	Has basis of strength substance (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride monohydrate (substance)	Is a	False	Donepezil hydrochloride (substance)	Inferred relationship	Some
Donepezil hydrochloride 10 mg oral tablet	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 23 mg oral tablet	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 5 mg oral tablet	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride monohydrate (substance)	Is modification of (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Some
Product containing precisely donepezil hydrochloride 10 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Product containing precisely donepezil hydrochloride 10 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has basis of strength substance (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 1 mg/mL oral solution	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 1 mg/mL oral solution	Has basis of strength substance (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 5 mg orodispersible tablet	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil hydrochloride 5 mg orodispersible tablet	Has basis of strength substance (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1
Donepezil (as donepezil hydrochloride) 5 mg and memantine (as memantine hydrochloride) 10 mg oral tablet	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Some	1

Reference Sets

Belgian subset for AllergyIntolerance, causative agent, drug

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Id	Description	Lang	Type	Status	Case?	Module
1461034013	Donepezil hydrochloride (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1480971010	Donepezil hydrochloride	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
807141000172111	chlorhydrate de donépézil	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Belgian module (core metadata concept)
807151000172113	donepezilhydrochloride	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Belgian module (core metadata concept)