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372912004: Substance with 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor mechanism of action (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\HMG-CoA reductase inhibitor

\Drug or medicament (substance)\Cardiovascular agent (substance)\Antilipemic agent (substance)\HMG-CoA reductase inhibitor

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
HMG-CoA reductase inhibitor	Is a	Antilipemic agent (substance)	true	Inferred relationship	Some
HMG-CoA reductase inhibitor	Is a	Allergen class	false	Inferred relationship	Some
HMG-CoA reductase inhibitor	Is a	Drug allergen	false	Inferred relationship	Some
HMG-CoA reductase inhibitor	Is a	Enzyme inhibitor	true	Inferred relationship	Some
HMG-CoA reductase inhibitor	Has disposition (attribute)	HMG-CoA reductase inhibitor	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Lovastatin	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Cerivastatin (substance)	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Atorvastatin (substance)	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Pravastatin (substance)	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor adverse reaction (disorder)	Causative agent	True	HMG-CoA reductase inhibitor	Inferred relationship	Some	1
Allergy to 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor	Causative agent	False	HMG-CoA reductase inhibitor	Inferred relationship	Some
Simvastatin (substance)	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Fluvastatin (substance)	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Product containing 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (product)	Has active ingredient	True	HMG-CoA reductase inhibitor	Inferred relationship	Some	1
Rosuvastatin calcium (substance)	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Adverse reaction to statins	Causative agent	False	HMG-CoA reductase inhibitor	Inferred relationship	Some
Administration of prophylactic statin (procedure)	Direct substance	True	HMG-CoA reductase inhibitor	Inferred relationship	Some	1
Pitavastatin (substance)	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Administration of prophylactic statin (procedure)	Direct substance	False	HMG-CoA reductase inhibitor	Inferred relationship	Some	1
Allergy to 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor	Causative agent	True	HMG-CoA reductase inhibitor	Inferred relationship	Some	1
Rosuvastatin	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Myalgia caused by statin	Causative agent	True	HMG-CoA reductase inhibitor	Inferred relationship	Some	1
Fluvastatin sodium (substance)	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Cerivastatin sodium	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Pravastatin sodium	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Atorvastatin calcium	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Atorvastatin calcium trihydrate (substance)	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Rosuvastatin zinc	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Pitavastatin calcium	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some
Atorvastatin calcium anhydrous (substance)	Is a	True	HMG-CoA reductase inhibitor	Inferred relationship	Some

Reference Sets

Belgian subset for AllergyIntolerance, causative agent, drug

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Id	Description	Lang	Type	Status	Case?	Module
1211430010	HMG-CoA reductase inhibitor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
3520665017	Substance with 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor mechanism of action (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
4651375012	Statin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1587421000172113	inhibiteur de la 3-hydroxy-3-méthylglutaryl-coenzyme A réductase	fr	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	Belgian module (core metadata concept)
1587451000172119	substance avec un mécanisme d'action d'inhibiteur de la 3-hydroxy-3-méthylglutaryl-coenzyme A réductase	fr	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	Belgian module (core metadata concept)
1587471000172114	inhibiteur de l'HMG-CoA réductase	fr	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	Belgian module (core metadata concept)
1587411000172115	statine	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Belgian module (core metadata concept)
1587431000172111	3-hydroxy-3-methylglutaryl-co-enzym-A-reductaseremmer	nl	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	Belgian module (core metadata concept)
1587441000172116	hydroxymethylglutarylco-enzym-A-reductaseremmer	nl	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	Belgian module (core metadata concept)
1587461000172117	HMG-CoA (hydroxymethylglutarylco-enzym-A)-reductaseremmer	nl	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	Belgian module (core metadata concept)