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372525000: Substance with hydrogen/potassium adenosine triphosphatase enzyme system inhibitor mechanism of action (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Hydrolase inhibitor\Proton pump inhibitor

\Drug or medicament (substance)\Gastrointestinal agent (substance)\Ulcer healing agent (substance)\Proton pump inhibitor

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Proton pump inhibitor	Is a	Ulcer healing agent (substance)	true	Inferred relationship	Some
Proton pump inhibitor	Is a	Allergen class	false	Inferred relationship	Some
Proton pump inhibitor	Is a	Drug allergen	false	Inferred relationship	Some
Proton pump inhibitor	Is a	Hydrolase inhibitor	true	Inferred relationship	Some
Proton pump inhibitor	Has disposition (attribute)	Proton pump inhibitor	true	Inferred relationship	Some
Proton pump inhibitor	Is a	Enzyme inhibitor	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Pantoprazole sodium	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Esomeprazole magnesium	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Proton pump inhibitor-containing product	Has active ingredient	True	Proton pump inhibitor	Inferred relationship	Some	1
Poisoning by magnesium trisilicate	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Bismuth compound poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Poisoning by histamine H2-receptor antagonists	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Antacid drug poisoning NOS	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
[X]Poisoning by other antacids and anti-gastric-secretion drugs	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Accidental bismuth compound poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Intentional bismuth compound poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Bismuth compound poisoning of undetermined intent	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Sucralfate poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Accidental sucralfate poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Intentional sucralfate poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
intoxication par le sucralfate d'intention indéterminée	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Misoprostol poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Accidental misoprostol poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Intentional misoprostol poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
intoxication par le misoprostol d'intention indéterminée	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Cimetidine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Accidental cimetidine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Intentional cimetidine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
intoxication par la cimétidine d'intention indéterminée	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Famotidine poisoning (disorder)	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Accidental famotidine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Intentional famotidine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
intoxication par la famotidine d'intention indéterminée	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Nizatidine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Accidental nizatidine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Intentional nizatidine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
intoxication par la nizatidine d'intention indéterminée	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Ranitidine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Accidental ranitidine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Intentional ranitidine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
intoxication par la ranitidine d'intention indéterminée	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Proton pump inhibitor poisoning	Causative agent	True	Proton pump inhibitor	Inferred relationship	Some	1
Carbenoxolone poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Accidental carbenoxolone poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Intentional carbenoxolone poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Carbenoxolone poisoning of undetermined intent	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Pirenzepine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Accidental pirenzepine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Intentional pirenzepine poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Pirenzepine poisoning of undetermined intent	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Accidental aluminum hydroxide poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Intentional aluminium hydroxide poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Aluminum hydroxide poisoning of undetermined intent	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Accidental magnesium trisilicate poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Intentional magnesium trisilicate poisoning	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Proton pump inhibitor adverse reaction	Causative agent	True	Proton pump inhibitor	Inferred relationship	Some	1
Allergy to H+/K+-exchanging ATPase inhibitor (finding)	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Proton pump inhibitor overdose	Causative agent	True	Proton pump inhibitor	Inferred relationship	Some	1
Poisoning by aluminum hydroxide	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Poisoning caused by antacid AND/OR antigastric secretion drug	Causative agent	False	Proton pump inhibitor	Inferred relationship	Some
Lansoprazole (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Rabeprazole sodium (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Omeprazole (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Pantoprazole (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Esomeprazole (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Rabeprazole (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Dexlansoprazole (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Allergy to H+/K+-exchanging ATPase inhibitor (finding)	Causative agent	True	Proton pump inhibitor	Inferred relationship	Some	1
Pantoprazole sodium sesquihydrate (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Esomeprazole magnesium dihydrate (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Esomeprazole magnesium trihydrate (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Esomeprazole sodium (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Omeprazole magnesium (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Omeprazole sodium	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Proton pump inhibitor therapy	Direct substance	True	Proton pump inhibitor	Inferred relationship	Some	1
Dexrabeprazole	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Dexrabeprazole sodium	Is a	True	Proton pump inhibitor	Inferred relationship	Some
Esomeprazole magnesium anhydrous (substance)	Is a	True	Proton pump inhibitor	Inferred relationship	Some

Reference Sets

Belgian subset for AllergyIntolerance, causative agent, drug

Description inactivation indicator reference set

GB English

US English

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Id	Description	Lang	Type	Status	Case?	Module
1211059016	Proton pump inhibitor	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3520657015	H+/K+-exchanging ATPase inhibitor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
3559308015	Substance with H+/K+-exchanging ATPase inhibitor mechanism of action	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
3779785019	Substance with hydrogen/potassium adenosine triphosphatase enzyme system inhibitor mechanism of action (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2466181000172114	H+/K+-ATP-ase-remmende stof	nl	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	Belgian module (core metadata concept)
2466191000172112	H+/K+-ATP-ase-remmer	nl	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	Belgian module (core metadata concept)
2466201000172110	waterstof-kalium-ATP-ase-remmer	nl	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	Belgian module (core metadata concept)
2466211000172113	stof met waterstof-kalium-ATP-ase-remmend werkingsmechanisme	nl	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	Belgian module (core metadata concept)