| Inbound Relationships | Type | Active | Source | Characteristic | Refinability | Group | 
| Palmoplantar keratoderma with leukoplakia | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Porokeratosis of Mibelli, superficial disseminated type | Associated morphology | False | Hyperkeratosis | Inferred relationship | Some | 6 | 
| Papillon-Lefèvre syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Papillon-Lefèvre syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Diffuse palmoplantar keratoderma of Thost-Unna (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Hereditary diffuse palmoplantar keratoderma (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Retention hyperkeratosis (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Retention hyperkeratosis due to neglect | Associated morphology | False | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Punctate palmoplantar keratoderma (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Superficial keratosis | Associated morphology | False | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Pretalar callosity (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Palmoplantar hyperkeratosis-hyperpigmentation syndrome of Cantu (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Cutaneous horn (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Callosity on hand (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Acquired palmoplantar keratoderma (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Plantar callosity (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Follicular atrophoderma with palmoplantar hyperkeratosis (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Follicular atrophoderma with palmoplantar hyperkeratosis (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Radiation-induced keratosis (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Tar keratosis (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Keratoderma blennorrhagicum (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Hidrotic ectodermal dysplasia syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Hidrotic ectodermal dysplasia syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Cole disease | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Cole disease | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Orthokeratosis | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Acral keratosis | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Acral keratosis | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Palmoplantar keratoderma | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Neu-Laxova syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Autosomal recessive palmoplantar keratoderma and congenital alopecia syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 4 | 
| Autosomal recessive palmoplantar keratoderma and congenital alopecia syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Autosomal dominant palmoplantar keratoderma and congenital alopecia (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 5 | 
| Autosomal dominant palmoplantar keratoderma and congenital alopecia (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 4 | 
| Woolly hair and palmoplantar keratoderma with dilated cardiomyopathy syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Woolly hair and palmoplantar keratoderma with dilated cardiomyopathy syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Haim Munk syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Ankylosing vertebral hyperostosis with tylosis syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 5 | 
| Ankylosing vertebral hyperostosis with tylosis syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Diffuse palmoplantar keratoderma and acrocyanosis syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Diffuse palmoplantar keratoderma and acrocyanosis syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Palmoplantar keratoderma, 46,XX sex reversal, predisposition to squamous cell carcinoma syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 4 | 
| Palmoplantar keratoderma, 46,XX sex reversal, predisposition to squamous cell carcinoma syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Palmoplantar keratoderma with deafness syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Palmoplantar keratoderma with deafness syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 5 | 
| Palmoplantar keratoderma Nagashima type (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Palmoplantar keratoderma Nagashima type (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Spastic paraplegia, intellectual disability, palmoplantar hyperkeratosis syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Spastic paraplegia, intellectual disability, palmoplantar hyperkeratosis syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Cerebral dysgenesis, neuropathy, ichthyosis, palmoplantar keratoderma syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Palmoplantar keratoderma with clinodactyly syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 4 | 
| Palmoplantar keratoderma with clinodactyly syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Arthrogryposis hyperkeratosis syndrome lethal form (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Naxos disease | Associated morphology | False | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Autosomal dominant diffuse palmoplantar keratoderma Norrbotten type (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Autosomal dominant diffuse palmoplantar keratoderma Norrbotten type (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Punctate palmoplantar keratoderma type 1 (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Punctate palmoplantar keratoderma type 1 (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Hereditary palmoplantar keratoderma Gamborg Nielsen type (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Hereditary palmoplantar keratoderma Gamborg Nielsen type (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Skin fragility, wooly hair, palmoplantar keratoderma syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 6 | 
| Skin fragility, wooly hair, palmoplantar keratoderma syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 5 | 
| Focal palmoplantar keratoderma with joint keratoses (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Diffuse palmoplantar keratoderma with painful fissures | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Autosomal dominant focal non-epidermolytic palmoplantar keratoderma with plantar blistering | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Leukoencephalopathy, palmoplantar keratoderma syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 4 | 
| Hypotrichosis, osteolysis, periodontitis, palmoplantar keratoderma syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 7 | 
| Hypotrichosis, osteolysis, periodontitis, palmoplantar keratoderma syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 8 | 
| Curly hair, acral keratoderma, caries syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 8 | 
| Curly hair, acral keratoderma, caries syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 7 | 
| Keratosis linearis, ichthyosis congenita, sclerosing keratoderma syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 4 | 
| Wooly hair with palmoplantar keratoderma syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Wooly hair with palmoplantar keratoderma syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 4 | 
| Striate palmoplantar keratoderma (disorder) | Associated morphology | False | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Striate palmoplantar keratoderma (disorder) | Associated morphology | False | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Nail and tooth abnormalities, marginal palmoplantar keratoderma, oral hyperpigmentation syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 8 | 
| Nail and tooth abnormalities, marginal palmoplantar keratoderma, oral hyperpigmentation syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 7 | 
| Punctate palmoplantar keratoderma type 2 (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 2 | 
| Hypohidrosis, enamel hypoplasia, palmoplantar keratoderma, intellectual disability syndrome (disorder) | Associated morphology | False | Hyperkeratosis | Inferred relationship | Some | 6 | 
| Corneal intraepithelial dyskeratosis, palmoplantar hyperkeratosis, laryngeal dyskeratosis syndrome | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 5 | 
| Porokeratosis of Mibelli, linear unilateral type | Associated morphology | False | Hyperkeratosis | Inferred relationship | Some | 6 | 
| Palmoplantar keratoderma, spastic paralysis syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Arsenical keratosis | Is a | True | Hyperkeratosis | Inferred relationship | Some |  | 
| Psoralen and long-wave ultraviolet radiation keratosis (morphologic abnormality) | Is a | True | Hyperkeratosis | Inferred relationship | Some |  | 
| Rough skin (finding) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Keratoderma due to Dowling-Meara type epidermolysis bullosa simplex (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Rough skin of hands | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Keratoderma hereditarium mutilans with ichthyosis syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 5 | 
| Keratoderma hereditarium mutilans with ichthyosis syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 6 | 
| Naxos disease | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 4 | 
| Keratitis ichthyosis and deafness syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Lymphedematous hyperkeratosis | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Keratosis | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Hyperkeratotic eczema of palms and soles | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 4 | 
| Hyperkeratotic eczema of soles | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Hypohidrosis, enamel hypoplasia, palmoplantar keratoderma, intellectual disability syndrome (disorder) | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Ulerythema of cheeks | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 4 | 
| Harlequin fetus | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 1 | 
| Hyperkeratotic eczema of palms | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Hyperkeratotic fissured eczema of palms | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 3 | 
| Hyperkeratotic eczema of palms and soles | Associated morphology | True | Hyperkeratosis | Inferred relationship | Some | 5 |