782977003: Larotrectinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Larotrectinib (substance)

\Drug or medicament (substance)\Antineoplastic agent (substance)\Larotrectinib (substance)
\Drug or medicament (substance)\Pyrazole derivative\Larotrectinib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\...

\Pyrimidine and/or pyrimidine derivative\Pyrimidine\Larotrectinib (substance)

\Azole\Pyrazole and/or pyrazole derivative (substance)\Pyrazole derivative\Larotrectinib (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Pyrimidine and/or pyrimidine derivative\Pyrimidine\Larotrectinib (substance)
\Organic compound\Organic cyclic compound\Heterocyclic compound\Azole\Pyrazole and/or pyrazole derivative (substance)\Pyrazole derivative\Larotrectinib (substance)
\Organic compound\Organic nitrogen compound\Pyrimidine and/or pyrimidine derivative\Pyrimidine\Larotrectinib (substance)
\Organic compound\Organic nitrogen compound\Azole\Pyrazole and/or pyrazole derivative (substance)\Pyrazole derivative\Larotrectinib (substance)
\Organic compound\Hydrocarbon\Pyrazole and/or pyrazole derivative (substance)\Pyrazole derivative\Larotrectinib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2019. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3757031016 Larotrectinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3757032011 Larotrectinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Larotrectinib (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Larotrectinib (substance)	Is a	Pyrazole derivative	true	Inferred relationship	Some
Larotrectinib (substance)	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Some
Larotrectinib (substance)	Has disposition (attribute)	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Some
Larotrectinib (substance)	Is a	Pyrimidine	true	Inferred relationship	Some
Larotrectinib (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing larotrectinib (medicinal product)	Has active ingredient	True	Larotrectinib (substance)	Inferred relationship	Some	1
Larotrectinib-containing product in oral dose form	Has active ingredient	True	Larotrectinib (substance)	Inferred relationship	Some	1
Product containing only larotrectinib in oral dose form (medicinal product form)	Has active ingredient	True	Larotrectinib (substance)	Inferred relationship	Some	1
Larotrectinib only product	Has active ingredient	True	Larotrectinib (substance)	Inferred relationship	Some	1
Larotrectinib sulfate	Is modification of (attribute)	True	Larotrectinib (substance)	Inferred relationship	Some
Larotrectinib (as larotrectinib sulfate) 20 mg/mL oral solution	Has basis of strength substance (attribute)	True	Larotrectinib (substance)	Inferred relationship	Some	1
Larotrectinib (as larotrectinib sulfate) 100 mg oral capsule	Has basis of strength substance (attribute)	True	Larotrectinib (substance)	Inferred relationship	Some	1
Product containing precisely larotrectinib (as larotrectinib sulfate) 25 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	True	Larotrectinib (substance)	Inferred relationship	Some	1

This concept is not in any reference sets