396026002: di-ethylstilbestrol (substantie)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with molecular messenger mechanism of action (substance)\Hormone\Sex hormone (substance)\Substance with estrogen receptor agonist mechanism of action (substance)\Diethylstilbestrol (substance)
\Substance categorized by disposition\Receptor agonist\Substance with estrogen receptor agonist mechanism of action (substance)\Diethylstilbestrol (substance)

\Drug or medicament (substance)\Hormone\Sex hormone (substance)\Substance with estrogen receptor agonist mechanism of action (substance)\Diethylstilbestrol (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Substance with phenol structure\Polyphenol (substance)\Diethylstilbestrol (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Diethylstilbestrol (substance)	Is a	oestrogeen	false	Inferred relationship	Some
Diethylstilbestrol (substance)	Has disposition (attribute)	oestrogeen	false	Inferred relationship	Some
Diethylstilbestrol (substance)	Has disposition (attribute)	Gonadal hormone	false	Inferred relationship	Some
Diethylstilbestrol (substance)	Is a	Substance with estrogen receptor agonist mechanism of action (substance)	true	Inferred relationship	Some
Diethylstilbestrol (substance)	Has disposition (attribute)	Estrogen receptor agonist	true	Inferred relationship	Some
Diethylstilbestrol (substance)	Is a	Polyphenol (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Stilboestrol adverse reaction	Causative agent	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Allergy to diethylstilbestrol (finding)	Causative agent	False	Diethylstilbestrol (substance)	Inferred relationship	Some
Stilbestrol [gynecological use]	Has active ingredient	False	Diethylstilbestrol (substance)	Inferred relationship	Some
Stilbestrol+lactic acid 500micrograms/5% pessary	Has active ingredient	False	Diethylstilbestrol (substance)	Inferred relationship	Some
Stilbestrol [malignancy]	Has active ingredient	False	Diethylstilbestrol (substance)	Inferred relationship	Some
Diethylstilbestrol 1 mg oral tablet	Has active ingredient	False	Diethylstilbestrol (substance)	Inferred relationship	Some
Product containing precisely diethylstilbestrol 5 milligram/1 each conventional release oral tablet (clinical drug)	Has active ingredient	False	Diethylstilbestrol (substance)	Inferred relationship	Some
Diethylstilbestrol diphosphate preparation	Has active ingredient	False	Diethylstilbestrol (substance)	Inferred relationship	Some
Diethylstilbestrol poisoning	Causative agent	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Product containing diethylstilbestrol (medicinal product)	Has active ingredient	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Product containing diethylstilbestrol and lactic acid (medicinal product)	Has active ingredient	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Diethylstilbestrol measurement	Component	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Allergy to diethylstilbestrol (finding)	Causative agent	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Exposure to diethylstilbestrol	Causative agent	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Fetal diethylstilbestrol syndrome (disorder)	Causative agent	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Diethylstilbestrol 1 mg oral tablet	Has active ingredient	False	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Diethylstilbestrol 1 mg oral tablet	Has basis of strength substance (attribute)	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Product containing precisely diethylstilbestrol 5 milligram/1 each conventional release oral tablet (clinical drug)	Has active ingredient	False	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Product containing precisely diethylstilbestrol 5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Exposure to diethylstilbestrol in utero (event)	Causative agent	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Fosfestrol tetrasodium (substance)	Is modification of (attribute)	False	Diethylstilbestrol (substance)	Inferred relationship	Some
Product containing precisely diethylstilbestrol 5 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Diethylstilbestrol 1 mg oral tablet	Has precise active ingredient	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Diethylstilbestrol-containing product in oral dose form	Has active ingredient	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Diethylstilbestrol only product	Has active ingredient	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Product containing only diethylstilbestrol and lactic acid (medicinal product)	Has active ingredient	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Diethylstilbestrol only product in oral dose form	Has active ingredient	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Fosfestrol (substance)	Is modification of (attribute)	True	Diethylstilbestrol (substance)	Inferred relationship	Some
Product containing only diethylstilbestrol in parenteral dose form (medicinal product form)	Has active ingredient	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Diethylstilbestrol-containing product in parenteral dose form	Has active ingredient	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
46,XX disorder of sex development caused by synthetic oral diethylstilbestrol	Causative agent	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Neonatal disorder caused by diethylstilbestrol transmitted via breast milk (disorder)	Causative agent	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1
Fetal disorder caused by diethylstilbestrol transmitted via placenta	Causative agent	True	Diethylstilbestrol (substance)	Inferred relationship	Some	1

Reference Sets

Dutch pathology simple reference set (foundation metadata concept)

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Id	Description	Lang	Type	Status	Case?	Module
1469966015	Diethylstilbestrol (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1477373011	Diethylstilbestrol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2475242013	Stilbestrol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4522311000146115	di-ethylstilbestrol (substantie)	nl	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4522331000146110	di-ethylstilbestrol	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4767441000146117	DES	nl	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
13086051000146113	Di-ethylstilbestrol; synthetisch hormoon, vroeger gebruikt ter voorkoming van miskramen; had soms borstkanker tot gevolg en leidde in de volgende generatie tot aandoeningen aan de geslachtsorganen.	nl	Definition	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)