387584000: simvastatine (substantie)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\HMG-CoA reductase inhibitor\Simvastatin (substance)

\Drug or medicament (substance)\Cardiovascular agent (substance)\Antilipemic agent (substance)\HMG-CoA reductase inhibitor\Simvastatin (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\...

\Organic acid and/or organic acid derivative\Carboxylic acid and/or carboxylic acid derivative (substance)\Carboxylic ester (substance)\Esterified fatty acid\Simvastatin (substance)

\Lipid\Esterified fatty acid\Simvastatin (substance)

\Ester\Carboxylic ester (substance)\Esterified fatty acid\Simvastatin (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Simvastatin (substance)	Is a	HMG-CoA reductase inhibitor	true	Inferred relationship	Some
Simvastatin (substance)	Has disposition (attribute)	HMG-CoA reductase inhibitor	true	Inferred relationship	Some
Simvastatin (substance)	Is a	Chemical categorized functionally	false	Inferred relationship	Some
Simvastatin (substance)	Is a	Esterified fatty acid	true	Inferred relationship	Some
Simvastatin (substance)	Is a	allergeen van geneesmiddel (substantie)	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Adverse reaction caused by simvastatin (disorder)	Causative agent	True	Simvastatin (substance)	Inferred relationship	Some	1
Allergy to simvastatin (finding)	Causative agent	False	Simvastatin (substance)	Inferred relationship	Some
Simvastatin 10 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Simvastatin 20 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Simvastatin 40 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Simvastatin 80 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Simvastatin 5 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Product containing simvastatin (medicinal product)	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Product containing ezetimibe and simvastatin (medicinal product)	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 10 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Ezetimibe 10 mg and simvastatin 20 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Ezetimibe 10 mg and simvastatin 40 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Ezetimibe 10 mg and simvastatin 80 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Product containing precisely simvastatin 80 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Simvastatin 40 mg orodispersible tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Product containing precisely simvastatin 10 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Simvastatin 20 mg orodispersible tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Nicotinic acid 1 g and simvastatin 20 mg prolonged-release oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Product containing precisely nicotinic acid 500 milligram and simvastatin 20 milligram/1 each prolonged-release oral tablet (clinical drug)	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Nicotinic acid 750 mg and simvastatin 20 mg prolonged-release oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some
Product containing nicotinic acid and simvastatin (medicinal product)	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	2
Allergy to simvastatin (finding)	Causative agent	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin-containing product in oral dose form	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 10 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 10 mg oral tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 20 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 20 mg oral tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 40 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 40 mg oral tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 80 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 80 mg oral tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 5 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 5 mg oral tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 10 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	2
Ezetimibe 10 mg and simvastatin 10 mg oral tablet	Has basis of strength substance (attribute)	False	Simvastatin (substance)	Inferred relationship	Some	2
Ezetimibe 10 mg and simvastatin 20 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	2
Ezetimibe 10 mg and simvastatin 20 mg oral tablet	Has basis of strength substance (attribute)	False	Simvastatin (substance)	Inferred relationship	Some	2
Ezetimibe 10 mg and simvastatin 40 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 40 mg oral tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 80 mg oral tablet	Has basis of strength substance (attribute)	False	Simvastatin (substance)	Inferred relationship	Some	2
Ezetimibe 10 mg and simvastatin 80 mg oral tablet	Has active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 80 mg oral tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 40 mg oral tablet	Has basis of strength substance (attribute)	False	Simvastatin (substance)	Inferred relationship	Some	2
Ezetimibe- and simvastatin-containing product in oral dose form	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 10 mg oral tablet	Has precise active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	2
Ezetimibe 10 mg and simvastatin 20 mg oral tablet	Has precise active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	2
Simvastatin 80 mg oral tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 80 mg oral tablet	Has precise active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	2
Simvastatin 5 mg oral tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 10 mg oral tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 20 mg oral tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 40 mg oral tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 40 mg oral tablet	Has precise active ingredient	False	Simvastatin (substance)	Inferred relationship	Some	2
Product containing only ezetimibe and simvastatin (medicinal product)	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Product containing only nicotinic acid and simvastatin (medicinal product)	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	2
Product containing only simvastatin (medicinal product)	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin only product in oral dose form	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe and simvastatin only product in oral dose form	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Nicotinic acid 1 g and simvastatin 20 mg prolonged-release oral tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	2
Nicotinic acid 1 g and simvastatin 20 mg prolonged-release oral tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	2
Nicotinic acid 750 mg and simvastatin 20 mg prolonged-release oral tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	2
Nicotinic acid 750 mg and simvastatin 20 mg prolonged-release oral tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	2
Product containing precisely nicotinic acid 500 milligram and simvastatin 20 milligram/1 each prolonged-release oral tablet (clinical drug)	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	2
Product containing precisely nicotinic acid 500 milligram and simvastatin 20 milligram/1 each prolonged-release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	2
Simvastatin 40 mg orodispersible tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 40 mg orodispersible tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Product containing precisely simvastatin 10 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Product containing precisely simvastatin 10 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Product containing precisely simvastatin 80 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Product containing precisely simvastatin 80 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 20 mg orodispersible tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 20 mg orodispersible tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Product containing nicotinic acid and simvastatin in oral dose form (medicinal product form)	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	2
Product containing simvastatin in oromucosal dose form (medicinal product form)	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Product containing only simvastatin in oromucosal dose form (medicinal product form)	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Nicotinic acid and simvastatin only product in oral dose form	Has active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	2
Ezetimibe 10 mg and simvastatin 10 mg oral tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 10 mg oral tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 20 mg oral tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 20 mg oral tablet	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 40 mg oral tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Ezetimibe 10 mg and simvastatin 80 mg oral tablet	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 4 mg/mL oral suspension	Has precise active ingredient	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin 4 mg/mL oral suspension	Has basis of strength substance (attribute)	True	Simvastatin (substance)	Inferred relationship	Some	1
Simvastatin therapy (procedure)	Direct substance	True	Simvastatin (substance)	Inferred relationship	Some	1

Reference Sets

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Id	Description	Lang	Type	Status	Case?	Module
1461762012	Simvastatin (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481674011	Simvastatin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4567101000146111	simvastatine	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4567111000146113	simvastatine (substantie)	nl	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)