387172005: fluoro-uracil (substantie)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Methyltransferase inhibitor\Thymidylate synthase inhibitor\Fluorouracil (substance)
\Substance categorized by disposition\Immunomodulator\Antimetabolite (substance)\Pyrimidine analog (substance)\Fluoropyrimidine (substance)\Fluorouracil (substance)

\Drug or medicament (substance)\Immunologic agent (substance)\Pyrimidine analog (substance)\Fluoropyrimidine (substance)\Fluorouracil (substance)
\Drug or medicament (substance)\Antineoplastic agent (substance)\Antimetabolite (substance)\Pyrimidine analog (substance)\Fluoropyrimidine (substance)\Fluorouracil (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Pyrimidine and/or pyrimidine derivative\Pyrimidine analog (substance)\Fluoropyrimidine (substance)\Fluorouracil (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Pyrimidine and/or pyrimidine derivative\Pyrimidine analog (substance)\Fluoropyrimidine (substance)\Fluorouracil (substance)
\Organic compound\Organic nitrogen compound\Pyrimidine and/or pyrimidine derivative\Pyrimidine analog (substance)\Fluoropyrimidine (substance)\Fluorouracil (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Fluorouracil (substance)	Is a	Pyrimidine analog (substance)	false	Inferred relationship	Some
Fluorouracil (substance)	Has disposition (attribute)	Antimetabolite (disposition)	true	Inferred relationship	Some
Fluorouracil (substance)	Is a	Fluoropyrimidine (substance)	true	Inferred relationship	Some
Fluorouracil (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Fluorouracil (substance)	Is a	Thymidylate synthase inhibitor	true	Inferred relationship	Some
Fluorouracil (substance)	Has disposition (attribute)	Thymidylate synthase inhibitor (disposition)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Fluorouracil measurement (procedure)	Component	True	Fluorouracil (substance)	Inferred relationship	Some	1
Accidental fluorouracil poisoning	Causative agent	False	Fluorouracil (substance)	Inferred relationship	Some
Intentional fluorouracil poisoning	Causative agent	False	Fluorouracil (substance)	Inferred relationship	Some
intoxicatie door fluorouracil met onbekende intentie	Causative agent	False	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil adverse reaction	Causative agent	True	Fluorouracil (substance)	Inferred relationship	Some	1
Allergy to fluorouracil	Causative agent	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil overdose	Causative agent	True	Fluorouracil (substance)	Inferred relationship	Some	1
Accidental fluorouracil overdose	Causative agent	True	Fluorouracil (substance)	Inferred relationship	Some	1
Intentional fluorouracil overdose	Causative agent	True	Fluorouracil (substance)	Inferred relationship	Some	1
overdosis fluoro-uracil met onbekende intentie	Causative agent	False	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing fluorouracil (medicinal product)	Has active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Poisoning by fluorouracil	Causative agent	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil 50 milligram/1 gram conventional release cutaneous cream (clinical drug)	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 25mg/mL injection solution 100mL vial	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 50mg/mL injection solution 50mL	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 25mg/mL injection solution 10mL vial	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 250 mg oral capsule	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 25mg/mL injection solution 20mL vial	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 25mg/mL infusion solution 200mL bottle	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 1% solution	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Product containing precisely fluorouracil 10 milligram/1 gram conventional release cutaneous cream (clinical drug)	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Product containing precisely fluorouracil 5 milligram/1 gram conventional release cutaneous cream (clinical drug)	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 20 mg/mL cutaneous solution	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 5% solution	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 50mg injection solution 100mL vial	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 50mg injection solution 10mL vial	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Product containing epinephrine and fluorouracil (medicinal product)	Has active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil 1g/20mL injection	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 500mg/10mL injection	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Trabeculectomy with intraoperative application of 5-fluorouracil (procedure)	Direct substance	True	Fluorouracil (substance)	Inferred relationship	Some	2
Accidental fluorouracil poisoning	Causative agent	True	Fluorouracil (substance)	Inferred relationship	Some	1
Intentional fluorouracil poisoning	Causative agent	True	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil (18-F) (substance)	Is a	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil sodium	Is a	False	Fluorouracil (substance)	Inferred relationship	Some
Trabeculectomy with intraoperative application of 5-fluorouracil (procedure)	Direct substance	False	Fluorouracil (substance)	Inferred relationship	Some	2
Allergy to fluorouracil	Causative agent	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing fluorouracil in parenteral dose form (medicinal product form)	Has active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing fluorouracil in topical dosage form	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 250 mg oral capsule	Has active ingredient	False	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil 250 mg oral capsule	Has basis of strength substance (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil sodium	Is modification of (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil (18-F) (substance)	Is modification of (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some
Fluorouracil 250 mg oral capsule	Has precise active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing fluorouracil in oral dose form (medicinal product form)	Has active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil 5 milligram/1 gram conventional release cutaneous cream (clinical drug)	Has basis of strength substance (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil 5 milligram/1 gram conventional release cutaneous cream (clinical drug)	Has precise active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil 10 milligram/1 gram conventional release cutaneous cream (clinical drug)	Has precise active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil 10 milligram/1 gram conventional release cutaneous cream (clinical drug)	Has basis of strength substance (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil 50 milligram/1 gram conventional release cutaneous cream (clinical drug)	Has precise active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil 50 milligram/1 gram conventional release cutaneous cream (clinical drug)	Has basis of strength substance (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil (as fluorouracil sodium) 2.5 gram/100 milliliter conventional release solution for injection vial	Has basis of strength substance (attribute)	False	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil (as fluorouracil sodium) 250 milligram/10 milliliter conventional release solution for injection vial	Has basis of strength substance (attribute)	False	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil (as fluorouracil sodium) 500 milligram/20 milliliter conventional release solution for injection vial	Has basis of strength substance (attribute)	False	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil (as fluorouracil sodium) 500 milligram/10 milliliter conventional release solution for injection vial	Has basis of strength substance (attribute)	False	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil (as fluorouracil sodium) 2.5 gram/50 milliliter conventional release solution for infusion vial	Has basis of strength substance (attribute)	False	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil-containing product in cutaneous dose form	Has active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Adrenaline and fluorouracil only product	Has active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing only fluorouracil (medicinal product)	Has active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil only product in cutaneous dose form	Has active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing only fluorouracil in parenteral dose form (medicinal product form)	Has active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil only product in oral dose form	Has active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil (as fluorouracil sodium) 25 mg/mL solution for injection	Has basis of strength substance (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil (as fluorouracil sodium) 50 mg/mL solution for infusion	Has basis of strength substance (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil (as fluorouracil sodium) 50 mg/mL solution for injection	Has basis of strength substance (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil 20 mg/mL cutaneous solution	Has precise active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil 20 mg/mL cutaneous solution	Has basis of strength substance (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some	1
FOLFIRI antineoplastic chemotherapy regimen	Direct substance	True	Fluorouracil (substance)	Inferred relationship	Some	2
FOLFIRINOX antineoplastic chemotherapy regimen	Direct substance	True	Fluorouracil (substance)	Inferred relationship	Some	2
Product containing precisely fluorouracil (as fluorouracil sodium) 50 milligram/1 milliliter conventional release solution for infusion and/or injection (clinical drug)	Has basis of strength substance (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some	1
Fluorouracil (as fluorouracil sodium) 25 mg/mL solution for infusion and/or injection	Has basis of strength substance (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil 5 milligram/1 gram and salicylic acid 100 milligram/1 gram conventional release cutaneous solution (clinical drug)	Has precise active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil 5 milligram/1 gram and salicylic acid 100 milligram/1 gram conventional release cutaneous solution (clinical drug)	Has basis of strength substance (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing only fluorouracil and salicylic acid (medicinal product)	Has active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil 40 milligram/1 gram conventional release cutaneous cream (clinical drug)	Has precise active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing precisely fluorouracil 40 milligram/1 gram conventional release cutaneous cream (clinical drug)	Has basis of strength substance (attribute)	True	Fluorouracil (substance)	Inferred relationship	Some	1
Product containing only fluorouracil and salicylic acid in cutaneous dose form (medicinal product form)	Has active ingredient	True	Fluorouracil (substance)	Inferred relationship	Some	1
Application of 5-fluorouracil to paranasal sinus (procedure)	Direct substance	True	Fluorouracil (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461350010	Fluorouracil (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481280012	Fluorouracil	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3721932017	5-fluorouracil	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4990241000146114	fluoro-uracil	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4990251000146112	fluoro-uracil (substantie)	nl	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4990261000146110	5-fluoro-uracil	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
11152321000146111	5-FU	nl	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)